Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6907335 | 0.74 | RAB9A (0.47) | RAB9ANPC1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL7522727 | 0.70 | RAB9A (0.54) | RAB9ANPC1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL8977355 | 0.70 | L3MBTL1 (0.31) | MEN1KMT2A | |
| SCHEMBL10561768 | 0.69 | DCUN1D1 (0.48) | ALDH1A1NPSR1 | |
| SCHEMBL28102440 | 0.68 | RAB9A (0.55) | RAB9ANPC1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL9460125 | 0.68 | MEN1 (0.39) | RAB9ANPC1ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL31241035 | 0.66 | NPC1 (0.62) | RAB9ANPC1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL31241087 | 0.66 | RAB9A (0.58) | RAB9ANPC1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL6907332 | 0.66 | ALDH1A1 (0.52) | RAB9ANPC1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL31241140 | 0.66 | RAB9A (0.73) | RAB9ANPC1ALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116418-A1 | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 2004-06-17 | — | — | US | disclosed |
| US-6376492-B1 | GUANIDINE DERIVATIVES | MEDIVIR AB (SE) | 2002-04-23 | — | — | US | disclosed |
| US-5849769-A | N-arylalkyl-N-heteroarylurea and guandine compounds and methods of treating HIV infection | MEDIVIR AB (SE) | 1998-12-15 | — | — | US | disclosed |
| EP-0706514-B1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1998-11-18 | — | — | EP | disclosed |