Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.45 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 7/20 | 0.41 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.36 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.36 |
| ▸ | GRM6 | O15303 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6906145 | 1.00 | TAS1R3 (0.45) | TAS1R3TAS1R1TAS1R2CCR2PCSK9 | |
| SCHEMBL6916637 | 0.90 | GRM2 (0.47) | ALDH1A1POLBMEN1KMT2ANPSR1 | |
| SCHEMBL6916632 | 0.90 | GRM2 (0.47) | ALDH1A1POLBMEN1KMT2ANPSR1 | |
| SCHEMBL6901988 | 0.90 | GRM2 (0.40) | TAS1R3TAS1R1TAS1R2NPSR1GRM2 | |
| SCHEMBL6901983 | 0.90 | GRM2 (0.40) | TAS1R3TAS1R1TAS1R2NPSR1GRM2 | |
| SCHEMBL6911749 | 0.90 | GRM2 (0.38) | TAS1R3TAS1R1ALDH1A1L3MBTL1GRM2 | |
| SCHEMBL6911744 | 0.90 | GRM2 (0.38) | TAS1R3TAS1R1ALDH1A1L3MBTL1GRM2 | |
| SCHEMBL6906235 | 0.88 | GRM2 (0.47) | TAS1R3TAS1R1ALDH1A1MEN1KMT2A | |
| SCHEMBL6906238 | 0.88 | GRM2 (0.47) | TAS1R3TAS1R1ALDH1A1MEN1KMT2A | |
| SCHEMBL6910269 | 0.88 | GRM2 (0.50) | TAS1R3TAS1R1TAS1R2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116489-A1 | Synthetic excitatory amino acids | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | disclosed |