SCHEMBL6906180

SCHEMBL6906180

C[Zr](C)(=[SiH2])(c1ccccc1)(c1ccccc1)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 6/20 0.33
HTR6 P50406 1/20 0.32
HTR2A P28223 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7605525 0.86 SIGMAR1 (0.33) SIGMAR1HTR6HTR2A
SCHEMBL5354275 0.82 HTR2A (0.35) SIGMAR1HTR6HTR2A
Hydrochloric Acid SCHEMBL9069920 0.80 HTR2A (0.34) SIGMAR1HTR6HTR2A
SCHEMBL6857340 0.79 HTR6 (0.32) SIGMAR1HTR6HTR2A
SCHEMBL7766831 0.79 SIGMAR1 (0.42) SIGMAR1HTR6HTR2A
SCHEMBL4428760 0.79 HTR2A (0.33) SIGMAR1HTR6HTR2A
SCHEMBL8678682 0.77 SIGMAR1 (0.31) SIGMAR1HTR6HTR2A
SCHEMBL797616 0.76 SIGMAR1 (0.32) SIGMAR1HTR2A
SCHEMBL7766805 0.76 HTR2A (0.35) SIGMAR1HTR6HTR2A
SCHEMBL7601481 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6410665-B1 POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN BASELL POLYOLEFINE GMBH (DE) 2002-06-25 US claimed
EP-0783022-B2 ETHYLENIC POLYMER COMPOSITION MITSUI CHEMICALS INC (JP) 2016-01-20 EP disclosed
EP-0783022-B1 ETHYLENIC POLYMER COMPOSITION MITSUI CHEMICALS INC (JP) 2004-09-22 EP disclosed
US-6410665-B1 POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN BASELL POLYOLEFINE GMBH (DE) 2002-06-25 US disclosed
EP-0719803-B1 Process for the production of cycloolefin random copolymer MITSUI CHEMICALS INC (JP) 2001-03-21 EP disclosed
US-6063871-A SPECIFIC HIGH-DENSITY ETHYLENE POLYMER AND A SPECIFIC ETHYLENE POLYMER, IN WHICH AT LEAST ONE IS PREPARED USING A METALLOCENE CATALYST, AND THE DENSITY RATIO THEREBETWEEN EXCEEDS 1; MOLDABILITY, CRACK RESISTANCE, STRENGTH AND RIGIDITY MITSUI PETROCHEMICAL INDUSTRIES, INC. (JP) 2000-05-16 US disclosed
EP-0570126-B1 Method for producing graft-modified copolymers MITSUBISHI CHEM CORP (JP) 1998-09-30 EP disclosed
US-5650471-A COPOLYMERIZING AN ALPHA-OLEFIN AND A CYCLOOLEFIN IN THE PRESENCE OF A CATALYST FORMED FROM A TRANSITION METAL COMPOUND AND AN ORGANIC ALUMINUM COMPOUND MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-07-22 US disclosed
EP-0783022-A1 ETHYLENIC POLYMER COMPOSITION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-07-09 EP disclosed
EP-0729983-A2 Process for the production of cycloolefin random copolymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-09-04 EP disclosed
EP-0719803-A2 Process for the production of cycloolefin random copolymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-07-03 EP disclosed
US-5334664-A Graft polymerization an unsaturated cyclic copolymer of propylene, bicycloheptene or tetracyclododecene with vinyl, vinylidene, unsaturated dicarboxylic acids or esters monomers MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) 1994-08-02 US disclosed
EP-0570126-A1 Method for producing graft-modified copolymers MITSUBISHI CHEMICAL CORPORATION (JP) 1993-11-18 EP disclosed