Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HRH2 | P25021 | 2/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL524090 | 0.79 | HRH2 (0.55) | HRH2HRH1SMN1; SMN2MAPTLMNA | |
| SCHEMBL524089 | 0.79 | HRH2 (0.55) | HRH2HRH1SMN1; SMN2MAPTLMNA | |
| SCHEMBL8382659 | 0.77 | EPHX1 (0.52) | ALDH1A1SMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL20434056 | 0.77 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL476725 | 0.76 | EPHX1 (0.47) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL459574 | 0.76 | EPHX1 (0.47) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL459573 | 0.76 | EPHX1 (0.47) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL6505996 | 0.76 | TSHR (0.47) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL10476064 | 0.74 | EPHX1 (0.46) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL7771457 | 0.74 | EPHX1 (0.46) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040023975-A1 | Pharmaceutical compositions for the treatment of systemic inflammatory response syndrome | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023975-A1 | Pharmaceutical compositions for the treatment of systemic inflammatory response syndrome | IL5, TSLP, TLR5 | ALDH1A1 1668/4885HRH2 77/4885HRH1 227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.