Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PELI1 | Q96FA3 | 2/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 10/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 10/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 5/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9246652 | 0.87 | ALOX5 (0.53) | PELI1ALPLALPIALPGDNMT1 | |
| SCHEMBL9468835 | 0.76 | POLB (0.51) | CYP3A4CYP2C9ALPLALPIALPG | |
| SCHEMBL9469098 | 0.76 | KDM4E (0.45) | HSD17B1HSD17B2ALPLALPIALPG | |
| SCHEMBL8365855 | 0.74 | ALOX5 (0.52) | PELI1ESR1ESR2MAOAUGT1A1 | |
| SCHEMBL726334 | 0.74 | POLB (0.47) | ALPLALPIALPGDNMT1MCL1 | |
| SCHEMBL17754365 | 0.74 | PELI1 (0.61) | PELI1HSD17B1HSD17B2CYP3A4CYP2C9 | |
| SCHEMBL3163234 | 0.73 | MEN1 (0.42) | CYP3A4CYP2C9MCL1ESR1ESR2 | |
| SCHEMBL38660243 | 0.73 | HSD17B1 (0.67) | PELI1HSD17B1HSD17B2CYP3A4CYP2C9 | |
| SCHEMBL9721409 | 0.72 | ALOX5 (0.59) | PELI1ALPLALPIALPGDNMT1 | |
| SCHEMBL9460317 | 0.71 | POLB (0.41) | ALPLALPIALPGDNMT1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785235-B1 | Compatibilized blends of polyetherimides and liquid crystalline polyesters | GEN ELECTRIC (US) | 2004-03-31 | — | — | EP | disclosed |
| US-6570038-B1 | Phase transfer agent; reacting phosgene with sceondary amine | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2003-05-27 | — | — | US | disclosed |
| EP-0784051-B1 | Aqueous hexasubstituted guanidinium chlorides and methods for their preparation and use | GEN ELECTRIC (US) | 2002-08-07 | — | — | EP | disclosed |
| US-6235934-B1 | MIXTURE WITH IMIDE AND SOLVENT | GENERAL ELECTRIC COMPANY | 2001-05-22 | — | — | US | disclosed |
| US-5872294-A | Aqueous hexasubstituted guanidinium chlorides and methods for their preparation and use | GENERAL ELECTRIC COMPANY (US) | 1999-02-16 | — | — | US | disclosed |
| EP-0785235-A2 | Compatibilized blends of polyetherimides and liquid crystalline polyesters | GENERAL ELECTRIC COMPANY (US) | 1997-07-23 | — | — | EP | disclosed |
| EP-0784051-A1 | Aqueous hexasubstituted guanidinium chlorides and methods for their preparation and use | GENERAL ELECTRIC COMPANY (US) | 1997-07-16 | — | — | EP | disclosed |
| US-5633319-A | NON-DELAMINATING; LOW VISCOSITY, HIGH WORKABILITY | GENERAL ELECTRIC COMPANY (US) | 1997-05-27 | — | — | US | disclosed |
| US-5132423-A | Nucleophilic substitution reaction of alkali hydroxy- or mercaptoaromatic compound and heterocyclic substituted imide | GENERAL ELECTRIC COMPANY (US) | 1992-07-21 | — | — | US | disclosed |
| US-5116975-A | Bis(guanidinium)alkane salts as phase transfer catalysts | GENERAL ELECTRIC COMPANY (US) | 1992-05-26 | — | — | US | disclosed |
| EP-0254994-B1 | POLYETHERIMIDE BISHALOFORMATE COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 1992-02-05 | — | — | EP | disclosed |
| US-5081298-A | Bis(pentaalkylguanidinium) alkane salts as phase transfer catalysts | GENERAL ELECTRIC COMPANY (US) | 1992-01-14 | — | — | US | disclosed |
| US-4757150-A | Polyetherimide bisphenol compositions | GENERAL ELECTRIC COMPANY (US) | 1988-07-12 | — | — | US | disclosed |
| EP-0254994-A1 | Polyetherimide bishaloformate compositions | GENERAL ELECTRIC COMPANY (US) | 1988-02-03 | — | — | EP | disclosed |