Sugi Predict

Sugi Predict / Compounds / SCHEMBL726334

SCHEMBL726334

SCHEMBL726334

O=S(=O)(c1ccc(O)cc1-c1ccccc1O)c1ccc(O)cc1-c1ccccc1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 2/20 0.47
▸ GAA P10253 1/20 0.47
▸ GFER P55789 1/20 0.47
▸ MCL1 Q07820 3/20 0.46
▸ ALPL P05186 1/20 0.46
▸ ALPI P09923 1/20 0.46
▸ ALPG P10696 1/20 0.46
▸ DNMT1 P26358 1/20 0.46
▸ TDP1 Q9NUW8 1/20 0.46
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ ESR2 Q92731 3/20 0.44
▸ ESR1 P03372 2/20 0.41
▸ MAOA P21397 1/20 0.41
▸ UGT1A1 P22309 1/20 0.41
▸ MAOB P27338 1/20 0.41
▸ BCL2 P10415 2/20 0.41
▸ HPGD P15428 2/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ TP53 P04637 1/20 0.40
▸ ALOX15 P16050 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2862404 0.85 MCL1 (0.54) POLBGAAGFERMCL1ALPL
SCHEMBL9459891 0.82 MIF (0.47) POLBGAAGFERMCL1ALPL
SCHEMBL9460317 0.82 POLB (0.41) POLBGAAGFERMCL1ALPL
SCHEMBL27672974 0.82 ALDH1A1 (0.44) POLBGAAGFERMCL1ALPL
SCHEMBL9246652 0.79 ALOX5 (0.53) POLBGAAGFERMCL1ALPL
SCHEMBL4636219 0.78 ESR2 (0.55) POLBGAAGFERTDP1L3MBTL1
SCHEMBL9250422 0.75 ALOX5 (0.62) POLBTDP1L3MBTL1ESR2ESR1
SCHEMBL7198840 0.75 ALDH1A1 (0.46) POLBGAAGFERMCL1ALPL
SCHEMBL6906342 0.74 PELI1 (0.49) MCL1ALPLALPIALPGDNMT1
SCHEMBL7893403 0.74 RNASEH1 (0.42) POLBGAAGFERMCL1ALPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3558250-A1 COMPOSITION COMPRISING A COMPOUND OF THIOLACTONE TYPE AND A PARTICULAR SOLVENT AND PROCESS FOR TREATING KERATIN MATERIALS WITH THE COMPOSITION L'Oréal (FR) 2019-10-30 — — EP claimed
WO-2018115273-A1 COMPOSITION COMPRISING A COMPOUND OF THIOLACTONE TYPE AND A PARTICULAR SOLVENT AND PROCESS FOR TREATING KERATIN MATERIALS WITH THE COMPOSITION L'OREAL (FR) 2018-06-28 — — WO claimed
US-9580615-B2 Phase change inks comprising inorganic nucleating agents XEROX CORPORATION (US) 2017-02-28 — — US claimed
US-8814999-B2 Phase change ink compositions comprising crystalline sulfone compounds and derivatives thereof XEROX CORPORATION (US) 2014-08-26 — — US claimed
US-20130284062-A1 PHASE CHANGE INK COMPOSITIONS COMPRISING CRYSTALLINE SULFONE COMPOUNDS AND DERIVATIVES THEREOF XEROX CORPORATION (US) 2013-10-31 — — US claimed
JP-4746237-B2 — — 2011-08-10 — — JP claimed
US-7375178-B2 High refractive index thermoplastic polyphosphonates ESSILOR INTERNATIONAL (FR) 2008-05-20 — — US claimed
US-20050101755-A1 HIGH REFRACTIVE INDEX THERMOPLASTIC POLYPHOSPHONATES JOHNSON & JOHNSON VISION CARE, INC. 2005-05-12 — — US claimed
EP-1254190-A4 HIGH REFRACTIVE INDEX THERMOPLASTIC POLYPHOSPHONATES JOHNSON & JOHNSON VISION CARE (US) 2005-04-13 — — EP claimed
EP-1254190-A1 HIGH REFRACTIVE INDEX THERMOPLASTIC POLYPHOSPHONATES Johnson & Johnson Products, Inc. (US) 2002-11-06 — — EP claimed
US-20020058779-A1 High refractive index thermoplastic polyphosphonates JOHNSON & JOHNSON VISION PRODUCTS, INC., AND VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. 2002-05-16 — — US claimed
WO-2001034683-A1 HIGH REFRACTIVE INDEX THERMOPLASTIC POLYPHOSPHONATES JOHNSON & JOHNSON PRODUCTS, INC. (US) 2001-05-17 — — WO claimed
US-20200031796-A1 COMPOSITION COMPRISING A COMPOUND OF THIOLACTONE TYPE AND A PARTICULAR SOLVENT AND PROCESS FOR TREATING KERATIN MATERIALS WITH THE COMPOSITION L'OREAL (FR) 2020-01-30 — — US disclosed
EP-3558250-A1 COMPOSITION COMPRISING A COMPOUND OF THIOLACTONE TYPE AND A PARTICULAR SOLVENT AND PROCESS FOR TREATING KERATIN MATERIALS WITH THE COMPOSITION L'Oréal (FR) 2019-10-30 — — EP disclosed
US-10292920-B2 Composition for dyeing keratin fibers L'OREAL (FR) 2019-05-21 — — US disclosed
US-20180353412-A1 COMPOSITIONS FOR DYEING KERATIN FIBERS L'OREAL (FR) 2018-12-13 — — US disclosed
US-6288210-B1 POLYTHIOPHOSPHONATES; OPHTHALMIC LENSES VIRGINIA TECH. INTELLECTUAL PROPERTIES, INC. 2001-09-11 — — US disclosed
WO-2001060806-A2 SUBSTITUTED ARYLPYRAZINES NEUROGEN CORPORATION (US) 2001-08-23 — — WO disclosed
WO-2001034683-A1 HIGH REFRACTIVE INDEX THERMOPLASTIC POLYPHOSPHONATES JOHNSON & JOHNSON PRODUCTS, INC. (US) 2001-05-17 — — WO disclosed
EP-1060904-A2 A thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-12-20 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180353412-A1 COMPOSITIONS FOR DYEING KERATIN FIBERS KRT18, CUTA, DSG1 POLB 1746/4885GAA 4156/4885GFER 1485/4885
US-10292920-B2 Composition for dyeing keratin fibers KRT18, IK, S100A10 POLB 2884/4885GAA 4691/4885GFER 1295/4885
US-20200031796-A1 COMPOSITION COMPRISING A COMPOUND OF THIOLACTONE TYPE AND A PARTICULAR SOLVENT AND PROCESS FOR TREATING KERATIN MATERIALS WITH THE COMPOSITION KRT18, KRTCAP2, MUC1 POLB 2447/4885GAA 4428/4885GFER 1258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.