Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4837029 | 0.83 | KDM4E (0.61) | PTPN1HPGDKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL11830878 | 0.81 | PTPN1 (0.59) | PTPN1HPGDKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL9589188 | 0.81 | PTPN1 (0.59) | PTPN1HPGDKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL9536383 | 0.80 | ALDH1A1 (0.55) | PTPN1HPGDKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL2544352 | 0.80 | PTPN1 (0.54) | PTPN1HPGDKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL1317943 | 0.79 | SMN1; SMN2 (0.72) | PTPN1HPGDKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL30623333 | 0.79 | SMN1; SMN2 (0.72) | PTPN1HPGDKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL28183693 | 0.79 | PTPN1 (0.57) | PTPN1HPGDKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL7946816 | 0.79 | PTPN1 (0.57) | PTPN1HPGDKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL13674512 | 0.79 | PTPN1 (0.53) | PTPN1HPGDKDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113806-A1 | ARYLAMIDES AND METHODS OF USE THEREOF | GENZYME CORPORATION (US) | 2021-06-10 | — | — | WO | disclosed |
| WO-2020114150-A1 | SYNTHESIS METHOD FOR SYNTHESIZING CARBAMATE USING DIMETHYL SULFOXIDE YLIDE, AMINE AND CARBON DIOXIDE | 华南理工大学 | 2020-06-11 | — | — | WO | disclosed |
| US-6825296-B2 | COORDINATION CATALYSTS | THE UNIVERSITY OF HONG KONG (HK) | 2004-11-30 | — | — | US | disclosed |
| US-20030191015-A1 | Catalyst component for olefin polymerization | UNIVERSITY OF HONG KONG, THE (CN) | 2003-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191015-A1 | Catalyst component for olefin polymerization | CBR1, MSMO1, DUOX1 | PTPN1 3168/4885HPGD 1971/4885KDM4E 1916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.