Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2541643 | 0.80 | ENPP2 (0.59) | PTPN1KDM4EHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL6906641 | 0.80 | PTPN1 (0.61) | PTPN1KDM4EHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL2540632 | 0.80 | NPC1 (0.50) | PTPN1KDM4EHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL4837029 | 0.78 | KDM4E (0.61) | PTPN1KDM4EHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL2545544 | 0.77 | NPC1 (0.60) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL2538609 | 0.76 | ALDH1A1 (0.51) | KDM4EHPGDALDH1A1MAPTHDAC1 | |
| SCHEMBL5702436 | 0.76 | MAPT (0.45) | SMN1; SMN2ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL9589188 | 0.76 | PTPN1 (0.59) | PTPN1KDM4EHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL2538592 | 0.76 | HDAC3 (0.56) | ALDH1A1MAPTCES2CES1HDAC1 | |
| SCHEMBL2536519 | 0.75 | ERCC5 (0.50) | HPGDALDH1A1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8044245-B2 | Method for the preparation of optically active 2-sulfonyloxy-1-phenylethanol derivatives | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2011-10-25 | — | — | US | disclosed |
| US-20100063317-A1 | METHOD FOR THE PREPARATION OF OPTICALLY ACTIVE 2-SULFONYLOXY-1-PHENYLETHANOL DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-03-11 | — | — | US | disclosed |
| WO-2008054155-A1 | METHOD FOR THE PREPARATION OF OPTICALLY ACTIVE 2-SULFONYLOXY-1-PHENYLETHANOL DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-05-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063317-A1 | METHOD FOR THE PREPARATION OF OPTICALLY ACTIVE 2-SULFONYLOXY-1-PHENYLETHANOL DERIVATIVES | FOXO1, ENO1, SULT1A1 | PTPN1 3519/4885KDM4E 2242/4885HPGD 1433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.