SCHEMBL6906824

SCHEMBL6906824

CCOC1COC(=O)c2ccc(cc2)C(=O)O1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
THRB P10828 1/20 0.31
MAPK1 P28482 1/20 0.31
GRM2 Q14416 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6904868 0.89 NPC1 (0.32) THRB
SCHEMBL28366854 0.81 ALDH1A1 (0.30) ALDH1A1
SCHEMBL28559908 0.75 CYP1A2 (0.33) THRBGRM2
SCHEMBL21037772 0.74
SCHEMBL2479036 0.74 MAOA (0.40)
SCHEMBL4719780 0.73 SIGMAR1 (0.32) ALDH1A1
SCHEMBL27100822 0.72 POLB (0.45)
SCHEMBL66015 0.71 MAOA (0.37) GRM2
SCHEMBL5779580 0.70
SCHEMBL4168935 0.69 GRM2 (0.37) GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0429311-B1 Polyester bottles ICI PLC (GB) 1998-01-14 EP claimed
US-5529744-A INJECTION MOLDING A THERMOPLASTIC POLYMER WHICH CONTAINS FINE METAL PARTICLES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1996-06-25 US claimed
US-5419936-A OF A POLYMER CONTAINING METAL PARTICLES WHICH ABSORB RADIATION IN A SPECIFIED WAVELENGTH REGION ICI CHEMICAL INDUSTRIES PLC (GB) 1995-05-30 US claimed
EP-0429311-A2 Polyester bottles IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-05-29 EP claimed
EP-0906356-B1 Process for producing a polyester polymer DUPONT TEIJIN FILMS US LTD (US) 2004-11-10 EP disclosed
EP-1082377-A1 METHOD OF PRODUCING A THERMOPLASTIC POLYMER PREFORM AND AN ARTICLE PRODUCED THEREFROM EASTMAN CHEMICAL COMPANY (US) 2001-03-14 EP disclosed
WO-1999061514-A1 METHOD OF PRODUCING A THERMOPLASTIC POLYMER PREFORM AND AN ARTICLE PRODUCED THEREFROM EASTMAN CHEMICAL COMPANY (US) 1999-12-02 WO disclosed
EP-0906356-A1 POLYESTER ARTICLE E.I. DU PONT DE NEMOURS & COMPANY INCORPORATED (US) 1999-04-07 EP disclosed
EP-0429311-B1 Polyester bottles ICI PLC (GB) 1998-01-14 EP disclosed
WO-1997047675-A1 POLYESTER ARTICLE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-12-18 WO disclosed
US-5529744-A INJECTION MOLDING A THERMOPLASTIC POLYMER WHICH CONTAINS FINE METAL PARTICLES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1996-06-25 US disclosed
US-5419936-A OF A POLYMER CONTAINING METAL PARTICLES WHICH ABSORB RADIATION IN A SPECIFIED WAVELENGTH REGION ICI CHEMICAL INDUSTRIES PLC (GB) 1995-05-30 US disclosed
EP-0429311-A2 Polyester bottles IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-05-29 EP disclosed