Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.58 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9748707 | 0.84 | CYP19A1 (0.66) | CYP19A1CHRNA7MEN1KMT2AMAPT | |
| SCHEMBL10830275 | 0.81 | MEN1 (0.67) | CYP19A1MEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL10988386 | 0.81 | CYP19A1 (0.76) | CYP19A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL330648 | 0.80 | NFKB1 (0.59) | MEN1KMT2AMAPTLMNAPOLB | |
| SCHEMBL10830031 | 0.79 | MEN1 (0.54) | CYP19A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL454232 | 0.78 | SLC5A1 (0.78) | CYP19A1MEN1KMT2AMAPTCYP3A4 | |
| Davidigenin SCHEMBL30291870 | 0.77 | CYP19A1 (0.70) | CYP19A1MEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL11431321 | 0.77 | NPC1 (0.69) | CYP19A1MEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL7187280 | 0.77 | CHRNA7 (0.71) | CYP19A1CHRNA7MAPTCYP3A4HPGD | |
| Davidigenin SCHEMBL750182 | 0.77 | CYP19A1 (0.70) | CYP19A1MEN1KMT2AMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040176471-A1 | Novel chalcone derivatives and pharmaceutical compositions comprising the same | KAOHSIUNG MEDICAL UNIVERSITY | 2004-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176471-A1 | Novel chalcone derivatives and pharmaceutical compositions comprising the same | PTGS1, PTGES2, PTGES | CYP19A1 103/4885CHRNA7 3981/4885MEN1 4271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.