Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.61 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.61 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30065457 | 0.87 | GAA (0.66) | CYP19A1GAAMAPTSLC5A1SLC5A2 | |
| SCHEMBL7301852 | 0.87 | GAA (0.66) | CYP19A1GAAMAPTSLC5A1SLC5A2 | |
| SCHEMBL6289452 | 0.84 | FFAR1 (0.61) | CYP19A1GAAMAPTSLC5A1SLC5A2 | |
| SCHEMBL10830275 | 0.84 | MEN1 (0.67) | CYP19A1GAAMAPTSLC5A1SLC5A2 | |
| SCHEMBL15650343 | 0.84 | RAB9A (0.55) | CYP19A1GAAMAPTSLC5A1SLC5A2 | |
| SCHEMBL6906879 | 0.84 | CYP19A1 (0.58) | CYP19A1GAAMAPTSLC5A1SLC5A2 | |
| SCHEMBL9061935 | 0.83 | ESR1 (0.59) | GAAMAPTCHRNA7ALOX5CA12 | |
| Dihydrochalcone SCHEMBL29359372 | 0.82 | CYP19A1 (0.80) | CYP19A1GAAMAPTSLC5A1SLC5A2 | |
| Dihydrochalcone SCHEMBL2827303 | 0.82 | CYP19A1 (0.80) | CYP19A1GAAMAPTSLC5A1SLC5A2 | |
| SCHEMBL9748469 | 0.82 | FFAR1 (0.58) | CYP19A1GAAMAPTSLC5A1SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120874-A | Process for the preparation of 5-hydroxydiprafenone and its acid addition salts | HELOPHARM W. PETRIK GMBH & CO. KG (DE) | 1992-06-09 | — | — | US | claimed |
| EP-0283540-B1 | PROCESS FOR THE PREPARATION OF 5-HYDROXYDIPRAPHENONE AND ITS SALTS WITH ACIDS | Helopharm W. Petrik GmbH & Co.KG. (DE) | 1991-09-18 | — | — | EP | claimed |
| EP-0283540-A1 | Process for the preparation of 5-hydroxydipraphenone and its salts with acids | Helopharm W. Petrik GmbH & Co.KG. (DE) | 1988-09-28 | — | — | EP | claimed |
| US-5120874-A | Process for the preparation of 5-hydroxydiprafenone and its acid addition salts | HELOPHARM W. PETRIK GMBH & CO. KG (DE) | 1992-06-09 | — | — | US | disclosed |
| EP-0283540-B1 | PROCESS FOR THE PREPARATION OF 5-HYDROXYDIPRAPHENONE AND ITS SALTS WITH ACIDS | Helopharm W. Petrik GmbH & Co.KG. (DE) | 1991-09-18 | — | — | EP | disclosed |
| EP-0283540-A1 | Process for the preparation of 5-hydroxydipraphenone and its salts with acids | Helopharm W. Petrik GmbH & Co.KG. (DE) | 1988-09-28 | — | — | EP | disclosed |