Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY1 | Q08828 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6908137 | 0.79 | NQO1 (0.35) | NQO1 | |
| SCHEMBL6908508 | 0.72 | NQO1 (0.38) | NQO1 | |
| SCHEMBL6908493 | 0.72 | MAPT (0.39) | MAPTNQO1 | |
| SCHEMBL5720233 | 0.58 | CYP3A4 (0.33) | — | |
| SCHEMBL6903133 | 0.56 | NQO1 (0.38) | NQO1 | |
| SCHEMBL21901185 | 0.55 | — | — | |
| Hydrochloric Acid SCHEMBL10821353 | 0.53 | NQO1 (0.94) | MAPTNQO1 | |
| SCHEMBL31265945 | 0.51 | NQO1 (0.46) | NQO1 | |
| SCHEMBL8761209 | 0.51 | — | — | |
| SCHEMBL2427349 | 0.50 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716999-B2 | REACTING 4-HALOACETOACETYL HALIDE IN A SOLVENT AND SCANDIUM TRIFLUOROMETHANESULFONATE (A LEWIS ACID) AND THEN HYDROLYZED TO FORM PYRONE DERIVATIVE | LONZA AG (CH) | 2004-04-06 | — | — | US | disclosed |
| US-20030013896-A1 | Pyrone derivatives and method for producing same | LONZA AG (CH) | 2003-01-16 | — | — | US | disclosed |
| EP-1235821-A2 | PYRONE DERIVATIVES AND A METHOD FOR PRODUCING SAME | Lonza AG (CH) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001040212-A2 | PYRONE DERIVATIVES AND A METHOD FOR PRODUCING SAME | LONZA AG (CH) | 2001-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013896-A1 | Pyrone derivatives and method for producing same | XDH, AMY1A, CA1 | ADCY1 24/4885MAPT 4448/4885HTT 4430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.