SCHEMBL6907006

SCHEMBL6907006

Fc1ccc2c(c1)Cc1ccccc1C2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
CYP1A2 P05177 3/20 0.42
CYP2A6 P11509 1/20 0.42
PARP1 P09874 2/20 0.41
MAPK1 P28482 1/20 0.41
DRD2 P14416 5/20 0.40
DRD1 P21728 4/20 0.40
DRD3 P35462 4/20 0.40
DRD5 P21918 3/20 0.40
ACHE P22303 1/20 0.39
KDM4E B2RXH2 1/20 0.39
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL2208350 0.90
Water SCHEMBL28759228 0.90
SCHEMBL5080927 0.84 ALDH1A1 (0.59) CA1CA2CA4CA6CYP1A2
SCHEMBL17068947 0.84 ALDH1A1 (0.59) CA1CA2CA4CA6CYP1A2
SCHEMBL29851576 0.84 ALDH1A1 (0.59) CA1CA2CA4CA6CYP1A2
SCHEMBL19810050 0.82 CYP1A2 (0.58) CA1CA2CA4CA6CYP1A2
SCHEMBL6557452 0.79 ALDH1A1 (0.53) CA1CA2CA4CA6CYP1A2
SCHEMBL577480 0.79 PGR (0.49) CA1CA2CA4CA6CYP1A2
SCHEMBL20123676 0.79 HSD17B3 (0.46) CA1CA2CA4CA6CYP1A2
SCHEMBL20123554 0.79 HSD17B3 (0.43) CA1CA2CA4CA6CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6815481-B2 FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-09 US disclosed
US-20020032256-A1 Polybutadiene composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-14 US disclosed