Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 1/20 | 0.38 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.38 |
| ▸ | DGKA | P23743 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 5/20 | 0.34 |
| ▸ | TLR2 | O60603 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL984668 | 0.80 | DGKA (0.34) | DGKACNR2TLR2ESR1S1PR4 | |
| SCHEMBL39389 | 0.76 | DGKA (0.37) | DGKACNR2TLR2ESR1S1PR4 | |
| SCHEMBL21176407 | 0.76 | DGKA (0.37) | DGKACNR2TLR2ESR1S1PR4 | |
| SCHEMBL26025226 | 0.73 | CNR2 (0.37) | DGKACNR2TLR2S1PR4S1PR1 | |
| SCHEMBL10030180 | 0.72 | DGKA (0.61) | DGKACNR2PLA2G4B | |
| SCHEMBL12679255 | 0.71 | MEN1 (0.35) | GABBR2GABBR1ESR1 | |
| SCHEMBL251619 | 0.70 | CNR2 (0.38) | DGKACNR2S1PR4S1PR1S1PR3 | |
| SCHEMBL6025323 | 0.70 | DGKA (0.38) | DGKACNR2TLR2ELANEESR1 | |
| SCHEMBL13525823 | 0.69 | ALDH2 (0.35) | GABBR2GABBR1CNR2TLR2 | |
| SCHEMBL7562130 | 0.69 | ALDH2 (0.45) | DGKACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6790499-B2 | ADDITIVE COMBINATION COMPRISES AT LEAST 2 COMPOUNDS SELECTED FROM (I.) POLY(VINYL ALCOHOL) OR ETHYLENE/VINYL ALCOHOL COPOLYMER, (II.) POLYHYDRIC ALCOHOLS AND (III.) POLYACRYLAMIDE, POLYMETHACRYLAMIDE OR COPOLYMERS | CIBA SPEICALTY CHEMICALS CORPORATION | 2004-09-14 | — | — | US | disclosed |