Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 3/20 | 0.33 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13738907 | 0.86 | DGKA (0.40) | DGKAS1PR1S1PR4S1PR3CNR2 | |
| SCHEMBL7576873 | 0.76 | DGKA (0.38) | DGKAS1PR1S1PR4S1PR3CNR2 | |
| SCHEMBL4447713 | 0.74 | MMP2 (0.41) | DGKAS1PR1CNR2TP53TSHR | |
| SCHEMBL6907103 | 0.70 | GABBR2 (0.38) | DGKAS1PR1S1PR4S1PR3CNR2 | |
| SCHEMBL3230032 | 0.69 | DGKA (0.66) | DGKATP53TSHRPLA2G4B | |
| SCHEMBL5350282 | 0.69 | DGKA (0.66) | DGKATP53TSHRPLA2G4B | |
| SCHEMBL5351714 | 0.69 | DGKA (0.66) | DGKATP53TSHRPLA2G4B | |
| SCHEMBL5352197 | 0.69 | DGKA (0.66) | DGKATP53TSHRPLA2G4B | |
| SCHEMBL5354673 | 0.69 | DGKA (0.66) | DGKATP53TSHRPLA2G4B | |
| SCHEMBL11713345 | 0.69 | DGKA (0.66) | DGKATP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592664-B1 | GRAFTABLE HINDERED AMINE LIGHT STABILIZERS | CIBA SC HOLDING AG (CH) | 2006-08-23 | — | — | EP | disclosed |