SCHEMBL6907124

SCHEMBL6907124

CCCCC1=Cc2ccccc2C1[Ti](Cl)(Cl)(=C(C)C)C1C(CCCC)=Cc2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
TSHR P16473 1/20 0.34
CYP2C19 P33261 1/20 0.34
TDP1 Q9NUW8 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6909988 0.85 PTGS2 (0.31) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL6902659 0.83 CYP3A4 (0.31) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL8356893 0.81 CYP3A4 (0.30) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
Hydrochloric Acid SCHEMBL8356895 0.77 CYP3A4 (0.31) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL10644406 0.74 TSHR (0.36) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL820363 0.74 ALDH1A1 (0.31) TDP1
SCHEMBL7194669 0.74 CYP3A4 (0.32) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL29213166 0.72 BCHE (0.35) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL815618 0.72 BCHE (0.35) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL813275 0.72 CYP3A4 (0.33) CYP3A4CYP2D6CYP2C9TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6790917-B2 POLYMERIZING A VINYL COMPOUND IN PRESENCE OF A CATALYST OBTAINED BY COMBINING ORGANOTRANSITION METAL COMPOUND, AN ALUMINUM COMPUND OR ALUMOXANE AND A BORON COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-09-14 US disclosed
US-20020198340-A1 Process for producing vinyl compound polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-12-26 US disclosed