Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 4/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL6915194 | 0.97 | SLC6A9 (0.32) | SLC6A9ALDH2TAS1R3TAS1R1TAS1R2 | |
| Alcohol SCHEMBL6911143 | 0.92 | F2R (0.33) | SLC6A9TAS1R3TAS1R1TAS1R2ATM | |
| SCHEMBL6912535 | 0.92 | SLC6A9 (0.33) | SLC6A9 | |
| SCHEMBL6915088 | 0.90 | SLC6A9 (0.34) | SLC6A9TAS1R3TAS1R1TAS1R2L3MBTL1 | |
| SCHEMBL6912820 | 0.89 | F2R (0.33) | SLC6A9 | |
| SCHEMBL6911371 | 0.86 | TAS1R3 (0.32) | SLC6A9TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7196800 | 0.74 | GRIN2D (0.37) | ATML3MBTL1 | |
| SCHEMBL7196802 | 0.74 | GRIN2D (0.37) | ATML3MBTL1 | |
| SCHEMBL6915058 | 0.72 | — | — | |
| SCHEMBL6914326 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074333-A2 | PROCESS FOR HOMO- OR COPOLYMERIZATIONOF CONJUGATED OLEFINES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2004-09-02 | — | — | WO | disclosed |