⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9660089 | 0.83 | HPGD (0.42) | — | |
| SCHEMBL8348747 | 0.81 | CHRNB2 (0.41) | — | |
| SCHEMBL16270730 | 0.80 | — | — | |
| SCHEMBL11480809 | 0.79 | CHRNB2 (0.41) | — | |
| SCHEMBL13988089 | 0.78 | MGAM (0.30) | — | |
| SCHEMBL1742062 | 0.77 | — | — | |
| SCHEMBL13891868 | 0.77 | THRA (0.33) | — | |
| SCHEMBL12828404 | 0.77 | KMT2A (0.41) | — | |
| SCHEMBL17061007 | 0.76 | — | — | |
| SCHEMBL27285473 | 0.75 | TSHR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9968587-B2 | Heterocycle analogs of CAI-1 as agonists of quorum sensing in vibrio | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2018-05-15 | — | — | US | disclosed |
| US-20180078526-A1 | HETEROCYCLE ANALOGS OF CAI-1 AS AGONISTS OF QUORUM SENSING IN VIBRIO | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2018-03-22 | — | — | US | disclosed |
| US-20170190717-A1 | Compounds and Methods for Inhibition of Hedgehog Signaling and Phosphodiesterase | VANDERBILT UNIVERSITY | 2017-07-06 | — | — | US | disclosed |
| US-20160200678-A1 | HETEROCYCLE ANALOGS OF CAI-1 AS AGONISTS OF QUORUM SENSING IN VIBRIO | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2016-07-14 | — | — | US | disclosed |
| US-20130102650-A1 | ANTIMICROBIAL COMPOUNDS OF 1,4-NAPHTOQUINONE STRUCTURE | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2013-04-25 | — | — | US | disclosed |
| US-6747077-B2 | HINDERED AMINE | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-06-08 | — | — | US | disclosed |
| CN-1151197-C | Stable metallocene polyolefine | �������⻯ѧƷ�ع�����˾ | 2004-05-26 | — | — | CN | disclosed |
| US-6512029-B1 | Stabilized metallocene polyolefins | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-01-28 | — | — | US | disclosed |
| US-20020128406-A1 | PROCESS FOR POLYMERIZING UNSATURATED POLYALKYLPIPERIDINES | WILEN CARL-ERIC MAGNUS (FI) | 2002-09-12 | — | — | US | disclosed |
| US-20020077394-A1 | Stabilized metallocene polypropylene | CIBA SPECIALTY CHEMICALS CORP. | 2002-06-20 | — | — | US | disclosed |
| EP-0294333-A2 | Composition for cationic polymerisation with hardening agents therefor | CIBA-GEIGY AG (CH) | 1988-12-07 | — | — | EP | disclosed |
| EP-0153904-B1 | PROCESS FOR THE PREPARATION OF A PROTECTION LAYER OR A RELIEF PATTERN | CIBA-GEIGY AG (CH) | 1988-09-14 | — | — | EP | disclosed |
| EP-0272215-A2 | Process for obtaining images | CIBA-GEIGY AG (CH) | 1988-06-22 | — | — | EP | disclosed |
| EP-0094915-B1 | CURABLE COMPOSITIONS CONTAINING METALLOCEN COMPLEXES, ACTIVATED PRIMERS OBTAINED THEREFROM AND THEIR USE | CIBA-GEIGY AG (CH) | 1987-01-21 | — | — | EP | disclosed |
| EP-0126712-B1 | CURABLE COMPOSITION AND USE THEREOF | CIBA-GEIGY AG (CH) | 1986-12-10 | — | — | EP | disclosed |
| US-4624912-A | EXPOSURE TO ELECTRON OR ACTINIC RADIATION, THEN HEATING | CIBA-GEIGY CORPORATION (US) | 1986-11-25 | — | — | US | disclosed |
| EP-0182744-A2 | Radiation curable filled epoxy resin compositions and their use | CIBA-GEIGY AG (CH) | 1986-05-28 | — | — | EP | disclosed |
| EP-0153904-A2 | Process for the preparation of a protection layer or a relief pattern | CIBA-GEIGY AG (CH) | 1985-09-04 | — | — | EP | disclosed |
| EP-0126712-A1 | Curable composition and use thereof | CIBA-GEIGY AG (CH) | 1984-11-28 | — | — | EP | disclosed |
| EP-0094915-A2 | Curable compositions containing metallocen complexes, activated primers obtained therefrom and their use | CIBA-GEIGY AG (CH) | 1983-11-23 | — | — | EP | disclosed |