Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.46 |
| ▸ | ACHE | P22303 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6911891 | 0.88 | SIGMAR1 (0.49) | TMEM97SIGMAR1ACHEMEN1KMT2A | |
| SCHEMBL6910481 | 0.87 | MEN1 (0.44) | TMEM97SIGMAR1ACHEMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6911142 | 0.86 | MEN1 (0.44) | TMEM97SIGMAR1ACHEMEN1KMT2A | |
| SCHEMBL8818924 | 0.81 | ACHE (0.60) | TMEM97SIGMAR1ACHEMEN1KMT2A | |
| SCHEMBL6914483 | 0.78 | SIGMAR1 (0.47) | TMEM97SIGMAR1ACHEMEN1KMT2A | |
| SCHEMBL6912986 | 0.75 | HDAC8 (0.47) | ACHEBCHEPPARG | |
| SCHEMBL6911131 | 0.75 | SIGMAR1 (0.37) | TMEM97SIGMAR1ACHEMEN1KMT2A | |
| SCHEMBL6915496 | 0.75 | ACHE (0.49) | TMEM97SIGMAR1ACHEMEN1KMT2A | |
| SCHEMBL6905694 | 0.74 | OPRK1 (0.46) | MEN1KMT2APTPN1MAOBALDH1A1 | |
| Hydrochloric Acid SCHEMBL6912379 | 0.74 | SIGMAR1 (0.37) | TMEM97SIGMAR1ACHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112998-B1 | AMINE DERIVATIVES | POLA CHEM IND INC (JP) | 2004-12-08 | — | — | EP | disclosed |
| US-6586633-B1 | Antifungal agents | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2003-07-01 | — | — | US | disclosed |
| EP-1112998-A1 | AMINE DERIVATIVES | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2001-07-04 | — | — | EP | disclosed |