Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1586133 | 0.91 | HCRTR1 (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL14983126 | 0.91 | HCRTR1 (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL1670991 | 0.84 | HCRTR1 (0.61) | HCRTR1HCRTR2 | |
| SCHEMBL1586818 | 0.81 | TSHR (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL3409706 | 0.74 | HCRTR1 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL1672821 | 0.74 | HCRTR1 (0.58) | HCRTR1HCRTR2 | |
| SCHEMBL3409710 | 0.74 | HCRTR1 (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL1586911 | 0.73 | HCRTR1 (0.77) | HCRTR1HCRTR2 | |
| SCHEMBL1586284 | 0.72 | CHRNB2 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL14973635 | 0.72 | CHRNB2 (0.46) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2491031-B1 | FUSED HETEROCYCLIC COMPOUNDS AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2013-08-07 | — | — | EP | disclosed |
| WO-2011050202-A1 | FUSED HETEROCYCLIC COMPOUNDS AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-04-28 | — | — | WO | disclosed |