SCHEMBL1609497

SCHEMBL1609497

Cc1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.59
MAPT P10636 3/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
RAB9A P51151 3/20 0.59
KDM4E B2RXH2 3/20 0.59
HPGD P15428 3/20 0.59
NPC1 O15118 2/20 0.59
LMNA P02545 1/20 0.59
SRD5A2 P31213 1/20 0.52
CYP1A2 P05177 3/20 0.50
MAOA P21397 2/20 0.50
HTR2C P28335 2/20 0.50
HTR2B P41595 2/20 0.50
ADRA2A P08913 1/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A4 P31645 1/20 0.50
POLB P06746 1/20 0.50
GAA P10253 1/20 0.50
PKM P14618 1/20 0.50
CYP3A4 P08684 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31400232 1.00 ALDH1A1 (0.59) ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E
SCHEMBL547186 0.91 ALDH1A1 (0.53) ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E
SCHEMBL29633547 0.89 METAP1 (0.57) ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E
SCHEMBL4897556 0.89 METAP1 (0.57) ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E
SCHEMBL6905673 0.88 MAOA (0.67) ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E
SCHEMBL14183727 0.88 CYP1A2 (0.52) ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E
SCHEMBL21694418 0.86 METAP1 (0.52) ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E
SCHEMBL20198232 0.85 SRD5A2 (0.64) ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E
SCHEMBL2340135 0.84 ALDH1A1 (0.52) ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E
SCHEMBL6907672 0.84 ALDH1A1 (0.50) ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115792174-A Method for dividing hydrocarbon source rock deposition organic phase by using dibenzofuran and methylfluorene 中国石油化工股份有限公司 2023-03-14 CN claimed
US-5670681-A Process for preparing a carbon-bridged biscyclopentadiene compound HOECHST AKTIENGESELLSCHAFT (DE) 1997-09-23 US claimed
EP-0190946-B1 NOVEL CYCLIC HEXAPEPTIDE LHRH ANTAGONISTS MERCK & CO. INC. (US) 1993-01-20 EP claimed
EP-3164465-B1 IMPROVED PROCESSES FOR RECOVERING VALUABLE COMPONENTS FROM A CATALYTIC FAST PYROLYSIS PROCESS ANELLOTECH INC (US) 2025-10-29 EP disclosed
US-20250092315-A1 HEAT TREATMENT PRODUCT BY PROCESS FOR INCREASED PITCH YIELDS PNC BANK, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2025-03-20 US disclosed
CN-118900820-A Liquid organohydrogen carrier compositions comprising a mixture of benzyltoluene isomers and methods of storing and releasing hydrogen using the same 汉阳大学校产学协力团 2024-11-05 CN disclosed
CN-118302504-A Preparation of renewable jet fuel from catalytic pyrolysis feedstock IFP 新能源公司 2024-07-05 CN disclosed
CN-118265764-A Preparation of renewable diesel from catalytic pyrolysis feedstock IFP 新能源公司 2024-06-28 CN disclosed
CN-117756967-A Silicon bridged metallocene catalyst and application thereof 上海化工研究院有限公司 2024-03-26 CN disclosed
CN-113443950-B Method for reducing carbonyl into methylene under illumination 中山大学 2023-11-03 CN disclosed
CN-115028522-B Preparation method of 2, 7-dihydroxy-9-fluorenone 杭州卢普生物科技有限公司 2023-10-24 CN disclosed
EP-0531443-A4 METHODS FOR TREATING INFLAMMATION AND COMPOUNDS AND COMPOSITIONS SUITABLE FOR USE THEREIN 1993-04-21 EP disclosed
EP-0532054-A1 Process for preparing alpha,alpha-disubstituted aromatics and heteroaromatics as cognition enhancers THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1993-03-17 EP disclosed
EP-0531443-A1 METHODS FOR TREATING INFLAMMATION AND COMPOUNDS AND COMPOSITIONS SUITABLE FOR USE THEREIN NOVA PHARMACEUTICAL CORPORATION (US) 1993-03-17 EP disclosed
EP-0190946-B1 NOVEL CYCLIC HEXAPEPTIDE LHRH ANTAGONISTS MERCK & CO. INC. (US) 1993-01-20 EP disclosed
US-5173489-A α,α-disubstituted aromatics and heteroaromatics as cognition enhancers THE DUPONT MERCK PHARMACEUTICAL CO. (US) 1992-12-22 US disclosed
US-5079260-A Side effect reduction; fluorene derivatives NOVA PHARMACEUTICAL CORPORATION (US) 1992-01-07 US disclosed
WO-1991018596-A1 METHODS FOR TREATING INFLAMMATION AND COMPOUNDS AND COMPOSITIONS SUITABLE FOR USE THEREIN WEITZBERG MOSHE (US) 1991-12-12 WO disclosed
US-4533670-A ANTIEPILEPTIC AGENTS ELI LILLY AND COMPANY (US) 1985-08-06 US disclosed
EP-0138415-A2 Fluorenylalkylimidazole derivatives ELI LILLY AND COMPANY (US) 1985-04-24 EP disclosed