Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 4/20 | 0.47 |
| ▸ | NADK | O95544 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | PI4KA | P42356 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.45 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.45 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.45 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.45 |
| ▸ | DNMT1 | P26358 | 4/20 | 0.44 |
| ▸ | DNMT3B | Q9UBC3 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6907874 | 1.00 | AHCY (0.47) | AHCYNADKADORA3TP53CYP2C9 | |
| SCHEMBL6908435 | 0.90 | AHCY (0.55) | AHCYNADKADORA3MAPK1MEN1 | |
| SCHEMBL6893039 | 0.90 | AHCY (0.55) | AHCYNADKADORA3MAPK1MEN1 | |
| SCHEMBL22875578 | 0.79 | ADORA1 (0.62) | ADORA3MAPK1MEN1ALDH1A1PI4KA | |
| SCHEMBL9218364 | 0.79 | ADORA1 (0.62) | ADORA3MAPK1MEN1ALDH1A1PI4KA | |
| SCHEMBL5822309 | 0.78 | ADORA3 (0.53) | ADORA3TP53CYP2C9NFKB1MAPK1 | |
| SCHEMBL5822306 | 0.78 | ADORA3 (0.53) | ADORA3TP53CYP2C9NFKB1MAPK1 | |
| SCHEMBL6907649 | 0.77 | AHCY (0.69) | AHCYNADKADORA3MAPK1MEN1 | |
| SCHEMBL23547954 | 0.76 | AHCY (0.58) | AHCYNADKADORA3MAPK1MEN1 | |
| SCHEMBL5794947 | 0.73 | ADORA1 (0.61) | AHCYNADKADORA3MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040043959-A1 | Combination therapies for treating methylthioadenosine phosphorylase deficient cells | AGOURON PHARMACEUTICALS INC. | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040043959-A1 | Combination therapies for treating methylthioadenosine phosphorylase deficient cells | APRT, MTAP, TYMP | AHCY 62/4885NADK 1514/4885ADORA3 743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.