Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6481161 | 0.88 | MEN1 (0.39) | TAAR1ALDH1A1SMN1; SMN2MAPK1POLB | |
| SCHEMBL6905404 | 0.88 | TAAR1 (0.43) | TAAR1ALDH1A1SMN1; SMN2MAPK1POLB | |
| SCHEMBL7081843 | 0.86 | TAAR1 (0.41) | TAAR1ALDH1A1SMN1; SMN2MAPK1POLB | |
| SCHEMBL6029625 | 0.76 | KMT2A (0.43) | ALDH1A1SMN1; SMN2MAPK1POLBNPC1 | |
| SCHEMBL6030456 | 0.74 | MEN1 (0.39) | TAAR1ALDH1A1SMN1; SMN2MAPK1POLB | |
| SCHEMBL6480485 | 0.74 | SMN1; SMN2 (0.37) | ALDH1A1SMN1; SMN2MAPK1POLBRAB9A | |
| SCHEMBL6030344 | 0.72 | CYP1A2 (0.48) | ALDH1A1SMN1; SMN2MAPK1MAPTMEN1 | |
| SCHEMBL6480960 | 0.71 | POLB (0.40) | ALDH1A1SMN1; SMN2MAPK1POLBNPC1 | |
| SCHEMBL6901764 | 0.70 | P2RX7 (0.40) | TAAR1SMN1; SMN2POLBRAB9ANPC1 | |
| SCHEMBL26608490 | 0.70 | POLB (0.54) | ALDH1A1SMN1; SMN2MAPK1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485355-A2 | PYRIDINYL AMIDES AND COMPOSITIONS THEREOF FOR USE AS FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003080576-A2 | PYRIDINYL AMIDES AND COMPOSITIONS THEREOF FOR USE AS FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-10-02 | — | — | WO | disclosed |