Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 6/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.32 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.31 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6031333 | 0.88 | S1PR1 (0.40) | SMN1; SMN2MAPK1ALDH1A1POLBP2RX3 | |
| SCHEMBL6030958 | 0.86 | MAPK1 (0.37) | SMN1; SMN2MAPK1ALDH1A1POLBP2RX3 | |
| SCHEMBL6029698 | 0.83 | KMT2A (0.52) | SMN1; SMN2MAPK1ALDH1A1KMT2A | |
| SCHEMBL6489914 | 0.82 | SLC6A9 (0.38) | MAPK1P2RX3P2RX2KMT2ANPC1 | |
| SCHEMBL6481161 | 0.75 | MEN1 (0.39) | SMN1; SMN2MAPK1ALDH1A1POLBKMT2A | |
| SCHEMBL6907976 | 0.74 | TAAR1 (0.41) | SMN1; SMN2MAPK1ALDH1A1POLBKMT2A | |
| SCHEMBL3457566 | 0.73 | S1PR3 (0.40) | P2RX3P2RX2BCL2BCL2L1MCL1 | |
| SCHEMBL6031138 | 0.70 | MEN1 (0.41) | KMT2AS1PR1S1PR3 | |
| SCHEMBL3456624 | 0.68 | KMT2A (0.56) | SMN1; SMN2MAPK1ALDH1A1KMT2A | |
| SCHEMBL68154 | 0.68 | SLC6A9 (0.38) | SMN1; SMN2MAPK1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050020643-A1 | Pyridinyl amides and compositions thereof for use as fungicides | E.I. DU PONT DE NEMOURS AND COMPANY | 2005-01-27 | — | — | US | disclosed |
| EP-1485355-A2 | PYRIDINYL AMIDES AND COMPOSITIONS THEREOF FOR USE AS FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003080576-A2 | PYRIDINYL AMIDES AND COMPOSITIONS THEREOF FOR USE AS FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-10-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020643-A1 | Pyridinyl amides and compositions thereof for use as fungicides | ME3, CYC1, ME2 | SMN1; SMN2 3884/4885MAPK1 1587/4885ALDH1A1 1201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.