Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8588672 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL937824 | 0.83 | GABRA1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL30525908 | 0.83 | GABRA1 (0.30) | — | |
| SCHEMBL7030163 | 0.77 | FABP3 (0.32) | — | |
| Hydrochloric Acid SCHEMBL5608996 | 0.77 | — | — | |
| SCHEMBL5355404 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL9421011 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL6519412 | 0.76 | — | — | |
| SCHEMBL388200 | 0.75 | — | — | |
| SCHEMBL8823400 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914376-A | Catalyst for the polymerization of olefins, process for the preparation thereof, and use thereof | TARGOR GMBH (DE) | 1999-06-22 | — | — | US | claimed |
| US-6747077-B2 | HINDERED AMINE | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-06-08 | — | — | US | disclosed |
| US-6512029-B1 | Stabilized metallocene polyolefins | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-01-28 | — | — | US | disclosed |
| US-20020128406-A1 | PROCESS FOR POLYMERIZING UNSATURATED POLYALKYLPIPERIDINES | WILEN CARL-ERIC MAGNUS (FI) | 2002-09-12 | — | — | US | disclosed |
| US-20020077394-A1 | Stabilized metallocene polypropylene | CIBA SPECIALTY CHEMICALS CORP. | 2002-06-20 | — | — | US | disclosed |
| US-20020013217-A1 | CATALYST FOR THE POLYMERIZATION OF OLEFINS, PROCESS FOR ITS PREPARATION AND ITS USE | HANS-FRIEDRICH HERRMANN | 2002-01-31 | — | — | US | disclosed |
| US-6051522-A | Catalyst which can be used for the preparation of olefins during polymerization | TARGOR GMBH (DE) | 2000-04-18 | — | — | US | disclosed |
| US-5955522-A | Process for the preparation of stabilized olefin polymers | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-09-21 | — | — | US | disclosed |
| US-5942586-A | Catalyst for the polymerization of olefins, process for its preparation and its use | TARGOR GMBH (DE) | 1999-08-24 | — | — | US | disclosed |
| US-5914376-A | Catalyst for the polymerization of olefins, process for the preparation thereof, and use thereof | TARGOR GMBH (DE) | 1999-06-22 | — | — | US | disclosed |
| US-5852142-A | Process for the preparation of an olefin polymer | TARGOR GMBH (DE) | 1998-12-22 | — | — | US | disclosed |
| US-5840948-A | Process for the preparation of substituted indenes and their use as ligand systems for metallocene catalysts | TARGOR GMBH (DE) | 1998-11-24 | — | — | US | disclosed |
| US-5703149-A | Process for the preparation of stabilized olefin polymers | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1997-12-30 | — | — | US | disclosed |
| EP-0567952-B1 | Olefin polymerization catalyst, process for its preparation, and its use | HOECHST AG (DE) | 1997-12-03 | — | — | EP | disclosed |
| US-5614455-A | Olefin polymerization catalyst, process for its preparation, and its use | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-25 | — | — | US | disclosed |
| US-5578537-A | Olefin polymerization catalyst process for its preparation and its use | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-11-26 | — | — | US | disclosed |
| EP-0578838-A1 | Olefin polymerization catalyst, process for its preparation, and its use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-01-19 | — | — | EP | disclosed |
| EP-0567952-A1 | Olefin polymerization catalyst, process for its preparation, and its use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |