Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.49 |
| ▸ | RXRB | P28702 | 2/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25909341 | 0.87 | RXRA (0.56) | RXRARXRBRXRGPTGS2PTPN5 | |
| SCHEMBL5352034 | 0.83 | RXRA (0.62) | RXRARXRBRXRGPTPN5CTSS | |
| SCHEMBL8676319 | 0.81 | RXRA (0.56) | RXRARXRBRXRGPTPN5CTSS | |
| SCHEMBL598181 | 0.81 | RXRA (0.66) | RXRARXRBRXRGPTPN5CTSS | |
| SCHEMBL6913011 | 0.80 | RXRA (0.49) | RXRARXRBRXRGPTGS2PTPN5 | |
| SCHEMBL598569 | 0.79 | CYP1A2 (0.45) | RXRARXRBRXRGPTGS2BCL2 | |
| SCHEMBL31190190 | 0.79 | CYP1A2 (0.45) | RXRARXRBRXRGPTGS2BCL2 | |
| SCHEMBL25909479 | 0.79 | RXRA (0.47) | RXRARXRBRXRGPTGS2PTPN5 | |
| Ethane SCHEMBL6908245 | 0.79 | RXRA (0.63) | RXRARXRBRXRGPTPN5CTSS | |
| SCHEMBL17810268 | 0.78 | PTGS2 (0.56) | RXRARXRBRXRGPTGS2PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100436490-C | Polymerization catalyst for alpha-olefin, novel transition metal compound and catalyst component, and process for producing polymer | MITSUBISHI CHEM CORP (JP) | 2008-11-26 | — | — | CN | disclosed |
| US-6825371-B2 | CATALYST FOR POLYMERIZATION OF ALPHA -OLEFIN, WHICH COMPRISES: AN ESSENTIAL COMPONENT (A) OF A TRANSITION METAL COMPOUND, AN ESSENTIAL COMPONENT (B) OF AN ION EXCHANGEABLE LAYER COMPOUND EXCEPT FOR SILICATE, OR AN INORGANIC SILICATE, AND OPTIONAL | MITSUBISHI CHEMICAL CORPORATION (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20030166459-A1 | Catalysts for polymerization of alpha-olefins, process for producing alpha-olefin polymers, novel transition metal compounds and catalyst components for polymerization of alpha-olefin | MITSUBISHI CHEMICAL CORPORATION | 2003-09-04 | — | — | US | disclosed |
| US-6590045-B2 | An alpha-olefin polymerization catalysts consists of a transition metal compound; an ion exchangable layer compound except for silicate, or an inorganic silicate | MITSUBISHI CHEMICAL CORPORATION (JP) | 2003-07-08 | — | — | US | disclosed |
| EP-1312619-A2 | Catalyst for the polymerisation of alpha olefins | Mitsubishi Chemical Corporation (JP) | 2003-05-21 | — | — | EP | disclosed |
| US-20020045535-A1 | Catalysts for polymerization of alpha-olefins, process for producing alpha-olefin polymers, novel transition metal compounds and catalyst components for polymerization of alpha-olefin | MITSUBISHI CHEMICAL CORPORATION. | 2002-04-18 | — | — | US | disclosed |
| US-6344530-B2 | POLYMERIZATION CATALYST OF A TRANSITION METAL COMPOUND, AN ION EXCHANGEABLE LAYER OR AN INORGANIC SILICATE AND AN ORGANOALUMINUM COMPOUND | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-02-05 | — | — | US | disclosed |
| US-6340652-B1 | AS POLYMERIZATION CATALYST | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-01-22 | — | — | US | disclosed |
| US-20010034425-A1 | Process for producing alpha-olefin polymers | MITSUBISHI CHEMICAL CORPORATION | 2001-10-25 | — | — | US | disclosed |
| US-6252097-B1 | Transition metal compounds | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-06-26 | — | — | US | disclosed |
| CN-1189506-A | Catalyst for polymerizing alpha-olefin, process for producing alpha-olefin polymer, novel transition metal compound for polymerizing alpha-olefin and catalyst component | MITSUBISHI CHEM CORP (JP) | 1998-08-05 | — | — | CN | disclosed |
| EP-0846696-A1 | Catalyst for polymerization of alpha-olefins | Mitsubishi Chemical Corporation (JP) | 1998-06-10 | — | — | EP | disclosed |