SCHEMBL6908320

SCHEMBL6908320

CC(F)C(F)C(O)(F)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26348128 0.76
SCHEMBL5382945 0.73
SCHEMBL737058 0.73
SCHEMBL26348110 0.72 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL3642868 0.67 SLC7A5 (0.31) ALDH1A1TSHR
SCHEMBL669549 0.65
Bicarbonate SCHEMBL8829543 0.64 TP53 (0.37) ALDH1A1TSHR
Trifluoroacetic Acid SCHEMBL27714775 0.64 TP53 (0.44) ALDH1A1TSHR
Trifluoroacetic Acid SCHEMBL3140803 0.64 TP53 (0.44) ALDH1A1TSHR
SCHEMBL31498018 0.63 SLC7A5 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6818423-B2 LOW-MOLECULAR-WEIGHT C4-C6-KETONES DERIVATIZED WITH REMOVABLE GROUP ARE REACTED WITH CYANIDE GROUP DONOR IN PRESENCE OF HYDROXYNITRILE LYASE OR BY RACEMIC REACTION, ACIDIC HYDROLYSIS, OPTIONALLY RESOLUTION, AND CLEAVAGE OF THE GROUP DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AU) 2004-11-16 US disclosed
US-20030092142-A1 Process for the preparation of chiral alpha-hydroxycarboxylic acids DSM FINE CHEMICALS AUSTRIA NFG GMBH & COKG (AT) 2003-05-15 US disclosed