SCHEMBL737058

SCHEMBL737058

O=C(O)C(O)(F)C(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5382945 1.00
Ether SCHEMBL7189239 0.80 KDM4E (0.32)
SCHEMBL322006 0.73
SCHEMBL26348128 0.73
SCHEMBL6908320 0.73 ALDH1A1 (0.35)
SCHEMBL6348790 0.71 ALDH1A1 (0.37)
SCHEMBL128482 0.71
SCHEMBL4712886 0.71 PKM (0.41)
Bicarbonate SCHEMBL27614276 0.69 CA1 (0.39)
Trifluoroacetic Acid SCHEMBL15321506 0.69 ALDH1A1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117946153-A Synthesis method of 3, 3-trifluoro lactic acid 四川富华信新材料科技有限公司 2024-04-30 CN claimed
US-10577456-B2 Halogenated cyclic diesters, related polymers, and methods for their preparation and use RATNER BUDDY D (US) 2020-03-03 US claimed
JP-4817600-B2 2011-11-16 JP claimed
EP-1434768-B1 ENHANCED SUBSTRATE IMAGING BY REVERSIBLE BINDING TO A PARAMAGNETIC COMPLEX BRACCO IMAGING SPA (IT) 2009-08-12 EP claimed
US-7005552-B2 Single reactor synthesis of KOH-capped polyols based on DMC-synthesized intermediates BAYER MATERIALSCIENCE LLC (US) 2006-02-28 US claimed
US-20050096488-A1 Single reactor synthesis of KOH-capped polyols based on DMC-synthesized intermediates COVESTRO LLC 2005-05-05 US claimed
EP-1528073-A1 Single reactor synthesis of polyols capped using basic catalysts and being based on intermediates synthesized using DMC-catalysts Bayer MaterialScience LLC (US) 2005-05-04 EP claimed
US-20040258618-A1 Enhanced substrate imaging by reversible binding to a paramagnetic complex BRACCO IMAGING S.P.A. (IT) 2004-12-23 US claimed
EP-1434768-A1 ENHANCED SUBSTRATE IMAGING BY REVERSIBLE BINDING TO A PARAMAGNETIC COMPLEX Bracco Imaging S.p.A. (IT) 2004-07-07 EP claimed
WO-2003033479-A1 ENHANCED SUBSTRATE IMAGING BY REVERSIBLE BINDING TO A PARAMAGNETIC COMPLEX BRACCO IMAGING S.P.A. (IT) 2003-04-24 WO claimed
EP-1302465-A1 Enhanced substrate imaging by reversible binding to a paramagnetic complex BRACCO IMAGING S.p.A. (IT) 2003-04-16 EP claimed
JP-5058954-A None JP disclosed
JP-5213821-A None JP disclosed
JP-5058955-A None JP disclosed
JP-6239797-A None JP disclosed
JP-H0558955-A PRODUCTION OF BETA-FLUORO-ALPHA-KETO ACID EQUIVALENT SUBSTANCE NIKKO KYODO CO LTD 1993-03-09 JP disclosed
JP-H0558954-A PRODUCTION OF TRIFLUOROLACTIC ACID DERIVATIVE NIKKO KYODO CO LTD 1993-03-09 JP disclosed
WO-1992020641-A1 OPTICALLY ACTIVE TRIFLUOROLACTIC ACID DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1992-11-26 WO disclosed
JP-H03148249-A PREPARATION OF 2-HYDROXY-3,3,3-TRIFLUOROPROPIONITRILE TOAGOSEI CHEM IND CO LTD 1991-06-25 JP disclosed
US-4103084-A ANTIBIOTICS GLAXO LABORATORIES LIMITED (GB) 1978-07-25 US disclosed