Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4452709 | 0.89 | TSHR (0.41) | THRBTSHRPOLBAPEX1HTT | |
| Methacrylic Acid SCHEMBL549170 | 0.84 | MAPT (0.39) | TSHRLMNAMAPTUSP2CYP3A4 | |
| SCHEMBL6211388 | 0.82 | THRB (0.52) | THRBTSHRPOLBAPEX1HTT | |
| Acetic Acid SCHEMBL2160838 | 0.82 | MAPT (0.40) | TSHRLMNAMAPTUSP2CYP3A4 | |
| Bicarbonate SCHEMBL29257315 | 0.80 | THRB (0.50) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL728980 | 0.80 | ALDH1A1 (0.35) | THRBTSHRLMNAMAPTUSP2 | |
| SCHEMBL809330 | 0.80 | THRB (0.53) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL16618079 | 0.80 | MAPT (0.44) | LMNAMAPTUSP2CYP3A4RECQL | |
| SCHEMBL18828 | 0.80 | — | — | |
| SCHEMBL6547122 | 0.79 | TSHR (0.56) | THRBTSHRPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040039090-A1 | Flame-resistant molding compositions | BAYER AKTIENGESELLSCHAFT (DE) | 2004-02-26 | — | — | US | disclosed |