Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6910165 | 0.84 | FGFR1 (0.33) | FGFR1FGFR2FGFR4FGFR3 | |
| Hydrochloric Acid SCHEMBL6911183 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL6905914 | 0.78 | MAPT (0.33) | HTTALDH1A1LMNAMAPTTDP1 | |
| Hydrochloric Acid SCHEMBL6910451 | 0.77 | BCHE (0.30) | — | |
| Hydrochloric Acid SCHEMBL6909993 | 0.71 | SMN1; SMN2 (0.33) | KDM4EALDH1A1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6908517 | 0.69 | GABRA1 (0.31) | HTTLMNAMAPT | |
| SCHEMBL27585047 | 0.68 | ACHE (0.33) | FGFR1FGFR2FGFR4FGFR3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27515758 | 0.67 | BCHE (0.32) | FGFR1FGFR2FGFR4FGFR3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6909569 | 0.67 | PDCD1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL6909241 | 0.64 | POLB (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6790917-B2 | POLYMERIZING A VINYL COMPOUND IN PRESENCE OF A CATALYST OBTAINED BY COMBINING ORGANOTRANSITION METAL COMPOUND, AN ALUMINUM COMPUND OR ALUMOXANE AND A BORON COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-09-14 | — | — | US | disclosed |
| US-20020198340-A1 | Process for producing vinyl compound polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-12-26 | — | — | US | disclosed |