Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.57 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6909959 | 0.94 | PGR (0.53) | PGRCNR2ADORA2BADORA1ADORA3 | |
| SCHEMBL24665898 | 0.90 | CYP1A2 (0.61) | PGRALDH1A1MEN1KMT2AGAA | |
| SCHEMBL5741928 | 0.86 | PGR (0.50) | PGRCNR2ADORA2BADORA1ADORA3 | |
| SCHEMBL16688540 | 0.86 | APEX1 (0.56) | PGRCNR2ADORA2BADORA1APEX1 | |
| SCHEMBL6421284 | 0.85 | CNR2 (0.57) | PGRCNR2ALDH1A1MEN1KMT2A | |
| SCHEMBL4668715 | 0.84 | CACNA1G (0.50) | PGRADORA2BADORA1ADORA2ASLC6A2 | |
| SCHEMBL25316072 | 0.84 | CNR2 (0.56) | PGRCNR2ALDH1A1MEN1KMT2A | |
| SCHEMBL30484776 | 0.84 | CNR2 (0.56) | PGRCNR2ALDH1A1MEN1KMT2A | |
| SCHEMBL25318908 | 0.84 | CNR2 (0.56) | PGRCNR2ALDH1A1MEN1KMT2A | |
| SCHEMBL8862370 | 0.84 | CNR2 (0.56) | PGRCNR2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039409-A2 | COMPOSITION COMPRISING ACTIVATORS OF IK POTASSIUM CHANNELS AND CALCINEURIN ANTAGONISTS AND USE THEREOF | SWITCH BIOTECH AG (DE) | 2004-05-13 | — | — | WO | claimed |
| CN-102675897-B | Thiourea/urea aromatic amine dye, as well as preparation method and application thereof | UNIV SHAANXI NORMAL | 2015-04-29 | — | — | CN | disclosed |
| CN-102675897-A | Thiourea/urea aromatic amine dye, as well as preparation method and application thereof | UNIV SHAANXI NORMAL | 2012-09-19 | — | — | CN | disclosed |
| WO-2004039409-A2 | COMPOSITION COMPRISING ACTIVATORS OF IK POTASSIUM CHANNELS AND CALCINEURIN ANTAGONISTS AND USE THEREOF | SWITCH BIOTECH AG (DE) | 2004-05-13 | — | — | WO | disclosed |