Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | HPD | P32754 | 4/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6909258 | 0.94 | PGR (0.57) | PGRALDH1A1CNR2KDM4EGAA | |
| SCHEMBL4621924 | 0.89 | ALDH1A1 (0.59) | PGRALDH1A1KDM4EGAAMAPT | |
| SCHEMBL6910089 | 0.89 | PGR (0.56) | PGRALDH1A1CNR2KDM4EGAA | |
| SCHEMBL8684650 | 0.85 | ALDH1A1 (0.47) | PGRALDH1A1KDM4EGAAMAPT | |
| SCHEMBL24665898 | 0.84 | CYP1A2 (0.61) | PGRALDH1A1GAA | |
| SCHEMBL12963428 | 0.84 | PGR (0.61) | PGRALDH1A1CNR2KDM4EGAA | |
| SCHEMBL5286253 | 0.82 | CYP1A2 (0.62) | ALDH1A1GAA | |
| SCHEMBL5741928 | 0.81 | PGR (0.50) | PGRALDH1A1CNR2KDM4EGAA | |
| SCHEMBL16688540 | 0.80 | APEX1 (0.56) | PGRALDH1A1CNR2GAAADORA2B | |
| SCHEMBL7291994 | 0.80 | TSHR (0.47) | PGRALDH1A1CNR2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039409-A2 | COMPOSITION COMPRISING ACTIVATORS OF IK POTASSIUM CHANNELS AND CALCINEURIN ANTAGONISTS AND USE THEREOF | SWITCH BIOTECH AG (DE) | 2004-05-13 | — | — | WO | claimed |
| WO-2004039409-A2 | COMPOSITION COMPRISING ACTIVATORS OF IK POTASSIUM CHANNELS AND CALCINEURIN ANTAGONISTS AND USE THEREOF | SWITCH BIOTECH AG (DE) | 2004-05-13 | — | — | WO | disclosed |