Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | ITPR3 | Q14573 | 5/20 | 0.32 |
| ▸ | ITPR2 | Q14571 | 2/20 | 0.32 |
| ▸ | ITPR1 | Q14643 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | INPP5A | Q14642 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL31621713 | 1.00 | — | — | |
| Phosphoric Acid SCHEMBL9451033 | 0.88 | — | — | |
| Phosphoric Acid SCHEMBL3788505 | 0.87 | CA2 (0.56) | CA2SLC34A1KDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL8851940 | 0.87 | CA2 (0.56) | CA2SLC34A1KDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL8844890 | 0.87 | CA2 (0.56) | CA2SLC34A1KDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL1332284 | 0.87 | — | — | |
| Phosphoric Acid SCHEMBL5907 | 0.87 | CA2 (0.56) | CA2SLC34A1KDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL36090 | 0.87 | CA2 (0.56) | CA2SLC34A1KDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL22 | 0.87 | — | — | |
| Phosphoric Acid SCHEMBL897840 | 0.87 | CA2 (0.56) | CA2SLC34A1KDM4EMMP2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1444290-A1 | COMPOSITIONS FOR AQUEOUS DELIVERY OF FLUORINATED SILANES | 3M Innovative Properties Company (US) | 2004-08-11 | — | — | EP | disclosed |
| WO-2003044075-A1 | COMPOSITIONS FOR AQUEOUS DELIVERY OF FLUORINATED SILANES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-05-30 | — | — | WO | disclosed |