Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | OXTR | P30559 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5090884 | 0.74 | OXTR (0.33) | KDM4EPKMOXTR | |
| SCHEMBL4660513 | 0.70 | KDM4E (0.37) | KDM4EPKMOXTR | |
| SCHEMBL17008829 | 0.69 | KDM4E (0.34) | KDM4EPKMOXTR | |
| SCHEMBL1507319 | 0.69 | OXTR (0.31) | KDM4EPKMOXTR | |
| SCHEMBL29387054 | 0.69 | KDM4E (0.39) | KDM4EPKMOXTR | |
| SCHEMBL251287 | 0.69 | KDM4E (0.39) | KDM4EPKMOXTR | |
| SCHEMBL5411844 | 0.68 | OXTR (0.33) | KDM4EPKMOXTR | |
| SCHEMBL2287265 | 0.67 | GAA (0.36) | KDM4EPKMHTR2CHTR2BOXTR | |
| SCHEMBL29842453 | 0.67 | GAA (0.36) | KDM4EPKMHTR2CHTR2BOXTR | |
| Ammonia Solution, Strong SCHEMBL7086115 | 0.67 | KDM4E (0.38) | KDM4EPKMOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923589-B1 | 3-HETEROATOM SUBSTITUTED CYCLOPENTADIENYL-CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC (US) | 2004-09-15 | — | — | EP | disclosed |
| US-6268444-B1 | TITANIUM, ZIRCONIUM OR HAFNIUM COMPOUNDS FOR POLYMERIZATION | DOW CHEMICAL COMPANY | 2001-07-31 | — | — | US | disclosed |