SCHEMBL2287265

SCHEMBL2287265

C1=CC2(C=Cc3ccccc32)c2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
OXTR P30559 1/20 0.33
KDM4E B2RXH2 1/20 0.33
PKM P14618 1/20 0.33
HSD11B1 P28845 1/20 0.31
HTR2C P28335 1/20 0.31
HTR2B P41595 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29842453 1.00 GAA (0.36) GAAMAPTOXTRKDM4EPKM
SCHEMBL8861340 0.75 OXTR (0.33) GAAMAPTOXTRKDM4EPKM
SCHEMBL29387054 0.74 KDM4E (0.39) GAAMAPTOXTRKDM4EPKM
SCHEMBL18573347 0.74 GAA (0.33) GAAMAPTOXTRKDM4EPKM
SCHEMBL22584880 0.74 GAA (0.33) GAAMAPTOXTRKDM4EPKM
SCHEMBL79022 0.74 KDM4E (0.39) GAAMAPTOXTRKDM4EPKM
SCHEMBL8984690 0.74 CACNB4 (0.35) GAAMAPTOXTRKDM4EPKM
SCHEMBL251287 0.74 KDM4E (0.39) GAAMAPTOXTRKDM4EPKM
Ammonia Solution, Strong SCHEMBL7086115 0.72 KDM4E (0.38) GAAMAPTOXTRKDM4EPKM
Hydrochloric Acid SCHEMBL349115 0.72 KDM4E (0.38) GAAMAPTOXTRKDM4EPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110041257-B Method for synthesizing indene spiro indene [1,2-c ] isoquinoline triketone compound 河南师范大学 2021-08-03 CN claimed
EP-2167481-B1 METHOD FOR PRODUCING PROPYLENE OXIDE SUMITOMO CHEMICAL CO (JP) 2011-10-12 EP claimed
US-20100197945-A1 METHOD FOR PRODUCING PROPYLENE OXIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-08-05 US claimed
US-20240110007-A1 PREPARATION OF POLY(CROWN ETHER)S SAUDI ARABIAN OIL COMPANY (SA) 2024-04-04 US disclosed
CN-110041257-B Method for synthesizing indene spiro indene [1,2-c ] isoquinoline triketone compound 河南师范大学 2021-08-03 CN disclosed
CN-110041257-B Method for synthesizing indene spiro indene [1,2-c ] isoquinoline triketone compound 河南师范大学 2021-08-03 CN disclosed
CN-110041257-B Method for synthesizing indene spiro indene [1,2-c ] isoquinoline triketone compound 河南师范大学 2021-08-03 CN disclosed
US-9790156-B2 Olefin hydroformylation methods for obtaining branched aldehydes LYONDELL CHEMICAL TECHNOLOGY, L.P. (US) 2017-10-17 US disclosed
CN-106660039-A Sulfonic acid-containing polymeric materials as amine adsorbents 3M创新有限公司 2017-05-10 CN disclosed
US-20170121262-A1 OLEFIN HYDROFORMYLATION METHODS FOR OBTAINING BRANCHED ALDEHYDES LYONDELL CHEMICAL TECHNOLOGY, L.P. (US) 2017-05-04 US disclosed
EP-2167481-B1 METHOD FOR PRODUCING PROPYLENE OXIDE SUMITOMO CHEMICAL CO (JP) 2011-10-12 EP disclosed
EP-0618496-A2 Photographic elements containing particular color couplers in combination with particular stabilizers EASTMAN KODAK COMPANY (US) 1994-10-05 EP disclosed
EP-0618497-A2 Photographic elements containing particular color couplers in combination with metal complex stabilizers EASTMAN KODAK COMPANY (US) 1994-10-05 EP disclosed
US-5350667-A Image forming silver halide emulsions with pyrazolone dyes EASTMAN KODAK COMPANY (US) 1994-09-27 US disclosed
EP-0605918-A2 Photographic material and process comprising a bicyclic pyrazolo coupler EASTMAN KODAK COMPANY (US) 1994-07-13 EP disclosed
EP-0602747-A2 Photographic material and process comprising a bicyclic pyrazolo coupler EASTMAN KODAK COMPANY (US) 1994-06-22 EP disclosed
EP-0602749-A1 Photographic material and process comprising a bicyclic pyrazolo coupler EASTMAN KODAK COMPANY (US) 1994-06-22 EP disclosed
EP-0602751-A1 Photographic material and process comprising a bicyclic pyrazolo coupler EASTMAN KODAK COMPANY (US) 1994-06-22 EP disclosed
EP-0602752-A1 Photographic material and process comprising a bicyclic pyrazolo coupler EASTMAN KODAK COMPANY (US) 1994-06-22 EP disclosed
WO-1993007534-A1 PHOTOGRAPHIC COLOUR COUPLERS AND PHOTOGRAPHIC MATERIALS CONTAINING THEM KODAK LIMITED (GB) 1993-04-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170121262-A1 OLEFIN HYDROFORMYLATION METHODS FOR OBTAINING BRANCHED ALDEHYDES HPD, ADH1A, ADH5 GAA 1893/4885MAPT 4406/4885OXTR 2132/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.