SCHEMBL6909558

SCHEMBL6909558

CCC(C(=O)O)c1cccc(Cl)c1Cl

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.63
KMT2A Q03164 2/20 0.63
TAS1R3 Q7RTX0 1/20 0.46
TAS1R1 Q7RTX1 1/20 0.46
TAS1R2 Q8TE23 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
NFKB1 P19838 1/20 0.46
PNMT P11086 1/20 0.46
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
GLA P06280 1/20 0.44
KCNQ2 O43526 2/20 0.44
TSHR P16473 1/20 0.43
CACNA1G O43497 1/20 0.42
CACNA2D1 P54289 1/20 0.42
CACNA1B Q00975 1/20 0.42
CACNB1 Q02641 1/20 0.42
CXCL8 P10145 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30821928 0.86 KCNQ2 (0.50) MEN1KMT2ACYP3A4CYP2D6NFKB1
SCHEMBL1489632 0.86 KCNQ2 (0.50) MEN1KMT2ACYP3A4CYP2D6NFKB1
SCHEMBL28563997 0.83 MEN1 (0.46) MEN1KMT2AKCNQ2AKR1C3AKR1C2
SCHEMBL22230493 0.83 MEN1 (0.46) MEN1KMT2ATAS1R3TAS1R1TAS1R2
SCHEMBL8675888 0.80 MEN1 (0.46) MEN1KMT2ATAS1R3TAS1R1TAS1R2
SCHEMBL6123354 0.79 KMT2A (0.62) MEN1KMT2ACYP1A2CYP3A4CYP2D6
SCHEMBL7825896 0.78 KMT2A (1.00) MEN1KMT2AALDH1A1LMNATSHR
SCHEMBL9770072 0.77 PNMT (0.55) MEN1KMT2ATAS1R3TAS1R1TAS1R2
SCHEMBL13186033 0.77 CXCL8 (0.68) MEN1KMT2ACYP3A4LMNAKCNQ2
SCHEMBL15568192 0.77 CXCL8 (0.59) MEN1KMT2ATAS1R3TAS1R1TAS1R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2782940-B1 PROCESS FOR THE PREPARATION OF A COPOLYMER OF ETHYLENE VERSALIS SPA (IT) 2018-03-21 EP claimed
EP-1113028-B1 Process for production of olefin polymer with long chain branching BAYER AG (US) 2004-03-31 EP claimed
EP-0950670-B1 Olefin polymerization process and catalyst system therefor BAYER INC (CA) 2002-03-27 EP claimed
EP-0546629-B1 Process for preparing elastomeric copolymers of ethylene with a high tensile strength of the crude product ENICHEM ELASTOMERS (IT) 1997-02-26 EP claimed
EP-0546629-A1 Process for preparing elastomeric copolymers of ethylene with a high tensile strength of the crude product ENICHEM ELASTOMERI S.r.l. (IT) 1993-06-16 EP claimed
CN-111499788-A Ethylene-propylene-non-conjugated diene copolymer and synthesis method thereof 中国石油天然气股份有限公司 2020-08-07 CN disclosed
US-20030114596-A1 Thermoplastic elastomer composition and ethylene-alpha-olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED 2003-06-19 US disclosed
US-6541592-B1 An ethylene- alpha -olefin copolymer (alpha -olefin having 3 to 8 carbon atoms and content from 20-33.7wt %), Moony viscosity ML1+4100 degree C. of from 20-60, tensile stress M100 of 2.5 Mpa; excellent flexability, and processability SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-04-01 US disclosed
EP-0660024-B1 Resin-coated pipe SUMITOMO CHEMICAL CO (JP) 1997-10-22 EP disclosed
EP-0546629-B1 Process for preparing elastomeric copolymers of ethylene with a high tensile strength of the crude product ENICHEM ELASTOMERS (IT) 1997-02-26 EP disclosed
US-5571585-A HAVING EXCELLENT PROCESSABILITY, MECHANICAL STRENGTH, NORMAL AND LOW TEMPERATURE IMPACT RESISTANCE, HEAT RESISTANCE, CHIPPING RESISTANCE AND COATING SURFACE APPEEARANCE SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-11-05 US disclosed
EP-0660024-A1 Resin-coated pipe SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-06-28 EP disclosed
EP-0546629-A1 Process for preparing elastomeric copolymers of ethylene with a high tensile strength of the crude product ENICHEM ELASTOMERI S.r.l. (IT) 1993-06-16 EP disclosed