Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6749148 | 0.79 | DRD2 (0.33) | ALDH1A1CYP1A2CYP2D6CYP2C19GAA | |
| SCHEMBL5679143 | 0.78 | DRD2 (0.33) | ALDH1A1CYP1A2CYP2D6CYP2C19GAA | |
| SCHEMBL6907620 | 0.78 | TSHR (0.35) | CACNA1GHTTALDH1A1MEN1KMT2A | |
| SCHEMBL6912076 | 0.77 | BCHE (0.38) | HTTALDH1A1MEN1KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL6851818 | 0.77 | CYP1A2 (0.32) | ALDH1A1CYP1A2CYP2D6CYP2C19GAA | |
| Hydrochloric Acid SCHEMBL6865425 | 0.77 | DRD2 (0.32) | ALDH1A1CYP1A2CYP2D6CYP2C19GAA | |
| Hydrochloric Acid SCHEMBL6865428 | 0.77 | CYP1A2 (0.32) | ALDH1A1CYP1A2CYP2D6CYP2C19GAA | |
| Hydrochloric Acid SCHEMBL6851816 | 0.77 | DRD2 (0.32) | ALDH1A1CYP1A2CYP2D6CYP2C19GAA | |
| SCHEMBL6910737 | 0.76 | DRD2 (0.40) | ALDH1A1CYP1A2KDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL6525880 | 0.76 | BCHE (0.38) | HTTALDH1A1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923589-B1 | 3-HETEROATOM SUBSTITUTED CYCLOPENTADIENYL-CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC (US) | 2004-09-15 | — | — | EP | disclosed |
| US-6268444-B1 | TITANIUM, ZIRCONIUM OR HAFNIUM COMPOUNDS FOR POLYMERIZATION | DOW CHEMICAL COMPANY | 2001-07-31 | — | — | US | disclosed |