SCHEMBL6909584

SCHEMBL6909584

CCOC(=O)CC1(C)C=Cc2cc(OC)ccc2C1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.40
HPGD P15428 6/20 0.40
HSD17B10 Q99714 4/20 0.40
KDM4E B2RXH2 4/20 0.40
GAA P10253 3/20 0.40
MAPT P10636 5/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
TSHR P16473 1/20 0.38
KMT2A Q03164 3/20 0.38
NPC1 O15118 3/20 0.38
USP2 O75604 2/20 0.38
RAB9A P51151 2/20 0.38
CASP1 P29466 2/20 0.38
OPRM1 P35372 1/20 0.38
NFKB1 P19838 1/20 0.38
NFKB2 Q00653 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6906401 0.85 HSD11B1 (0.40) ALDH1A1HPGDHSD17B10CYP1A2CYP2C19
SCHEMBL31484123 0.85 HSD11B1 (0.40) ALDH1A1HPGDHSD17B10CYP1A2CYP2C19
SCHEMBL9436899 0.85 HSD11B1 (0.40) ALDH1A1HPGDHSD17B10CYP1A2CYP2C19
SCHEMBL11271707 0.83 RYR2 (0.34) HSD17B10KDM4EGAAMAPTTSHR
SCHEMBL14303312 0.73 HTR2C (0.38)
SCHEMBL4966926 0.72 HTR5A (0.40) GAAOPRM1
SCHEMBL11459392 0.70 BRD4 (0.42) ALDH1A1HPGDHSD17B10KDM4EGAA
SCHEMBL10341539 0.70 SMN1; SMN2 (0.47) ALDH1A1HPGDHSD17B10KDM4EGAA
SCHEMBL19995876 0.68 KMT2A (0.41) ALDH1A1HPGDKDM4EGAAMAPT
SCHEMBL8096734 0.68 PPARG (0.42) ALDH1A1HPGDHSD17B10KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004065334-A1 METHOD OF REMOVING ORGANOTIN RESIDUE CHIROGEN PTY LIMITED (AU) 2004-08-05 WO disclosed
WO-2004065335-A1 ENANTIOSELECTIVE REDUCTION METHOD CHIROGEN PTY LIMITED (AU) 2004-08-05 WO disclosed