Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RYR2 | Q92736 | 1/20 | 0.34 |
| ▸ | POLA1 | P09884 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.33 |
| ▸ | FEN1 | P39748 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6906401 | 0.90 | HSD11B1 (0.40) | RYR2POLA1HSD11B1HSD17B10PTGS1 | |
| SCHEMBL9436899 | 0.90 | HSD11B1 (0.40) | RYR2POLA1HSD11B1HSD17B10PTGS1 | |
| SCHEMBL31484123 | 0.90 | HSD11B1 (0.40) | RYR2POLA1HSD11B1HSD17B10PTGS1 | |
| SCHEMBL6909584 | 0.83 | ALDH1A1 (0.40) | HSD17B10SMN1; SMN2MEN1LMNAGAA | |
| SCHEMBL14303312 | 0.74 | HTR2C (0.38) | — | |
| SCHEMBL4966926 | 0.73 | HTR5A (0.40) | GAA | |
| SCHEMBL8801459 | 0.64 | HTR2C (0.51) | RYR2MEN1LMNATSHRKMT2A | |
| SCHEMBL11471180 | 0.62 | ATM (0.40) | MTNR1AMTNR1BHSD17B10PTGS1AKR1C3 | |
| SCHEMBL1231040 | 0.61 | BCL2 (0.42) | HSD17B10 | |
| SCHEMBL6949352 | 0.61 | AKR1C2 (0.47) | MTNR1AHSD17B10PTGS1AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57149242-A | — | — | None | — | — | JP | disclosed |
| JP-S57149242-A | PREPARATION OF (+)-2-(6-METHOXY-2-NAPHTHYL)PROPIONIC ACID | HAMARI YAKUHIN KOGYO KK | 1982-09-14 | — | — | JP | disclosed |