Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28941567 | 0.86 | GSTP1 (0.38) | GSTP1SLC6A2SLC6A4SLC6A3HDAC4 | |
| SCHEMBL7601711 | 0.85 | GSTP1 (0.37) | GSTP1SLC6A2SLC6A4SLC6A3HDAC4 | |
| SCHEMBL5363333 | 0.84 | BRD4 (0.31) | — | |
| SCHEMBL215863 | 0.84 | BRD4 (0.32) | CHRNB2CHRNA4 | |
| SCHEMBL29442977 | 0.84 | BRD4 (0.32) | CHRNB2CHRNA4 | |
| SCHEMBL5351378 | 0.83 | ENPP3 (0.33) | METADORA1 | |
| Hydrochloric Acid SCHEMBL819254 | 0.83 | BRD4 (0.31) | CHRNB2CHRNA4 | |
| SCHEMBL2234309 | 0.83 | EDNRB (0.30) | — | |
| SCHEMBL1010160 | 0.82 | GSTP1 (0.36) | GSTP1SLC6A2SLC6A4SLC6A3HDAC4 | |
| SCHEMBL8675236 | 0.82 | BRD4 (0.38) | ALDH1A1NPC1MAPTRAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0836624-B1 | METHOD FOR PRODUCING PREPOLYMERIZED, SUPPORTED METALLOCENE CATALYST SYSTEMS | EXXONMOBIL CHEM PATENTS INC (US) | 2002-04-17 | — | — | EP | claimed |
| US-6787618-B1 | TRANSPARENT, STIFF MOLDING MATERIALS; IMPACT TOUGHNESS; FOOD PACKAGING | BASELL POLYPROPYLEN GMBH (DE) | 2004-09-07 | — | — | US | disclosed |
| US-6051727-A | A POLYMERIZATION CATALYST FOR POLYOLEFINS OF HIGH MOLECULAR WEIGHT, OF PARTICULAR IMPORTANCE FOR THE PRODUCTION OF FILMS, SHEETS OR LARGE HOLLOW ARTICLES OR MOLDINGS SUCH AS PIPES | TARGOR GMBH (DE) | 2000-04-18 | — | — | US | disclosed |