SCHEMBL6909731

SCHEMBL6909731

CC(C)C1=Cc2c(Cl)cccc2C1.Cc1ccccc1-c1cccc2c1C=C(C(C)C)C2

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
EIF2AK1 Q9BQI3 1/20 0.32
PLA2G7 Q13093 1/20 0.31
ELANE P08246 1/20 0.30
MGAM O43451 1/20 0.30
GAA P10253 1/20 0.30
SI P14410 1/20 0.30
MGAM2 Q2M2H8 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
HTR7 P34969 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6052968 0.92 HTR7 (0.34) MEN1KMT2AHTR7
SCHEMBL6648035 0.89
SCHEMBL5361006 0.85 CYP2D6 (0.33)
SCHEMBL6909850 0.82
SCHEMBL6647941 0.81
Lithium Ion SCHEMBL6907812 0.75
SCHEMBL31197637 0.75 PRCP (0.35) HTR7
SCHEMBL4467574 0.75 PRCP (0.35) HTR7
SCHEMBL4460798 0.74 HTR7 (0.38) GAAMEN1KMT2AHTR7
SCHEMBL6149919 0.70 BRD4 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1254186-B1 PROPYLENE IMPACT COPOLYMERS EXXONMOBIL CHEM PATENTS INC (US) 2004-12-29 EP disclosed