SCHEMBL4467574

SCHEMBL4467574

CC(C)C1=Cc2c(cccc2-c2ccccc2)C1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PRCP P42785 1/20 0.35
HTR1A P08908 2/20 0.34
HTR7 P34969 2/20 0.34
ANPEP P15144 2/20 0.33
IL1RN P18510 1/20 0.33
ERAP2 Q6P179 1/20 0.33
ERAP1 Q9NZ08 1/20 0.33
CDC25A P30304 1/20 0.33
CDC25B P30305 1/20 0.33
ADRA2A P08913 2/20 0.32
ADRA2B P18089 2/20 0.32
ADRA2C P18825 2/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
PDCD1 Q15116 1/20 0.32
CD274 Q9NZQ7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31197637 1.00 PRCP (0.35) PRCPHTR1AHTR7ANPEPIL1RN
SCHEMBL26606300 0.88 PNMT (0.31) MAOA
SCHEMBL29534991 0.83 BRD4 (0.34)
SCHEMBL4469441 0.83 GSTP1 (0.40) MAOB
SCHEMBL1808402 0.83 BRD4 (0.34)
SCHEMBL6052968 0.82 HTR7 (0.34) HTR1AHTR7CDC25ACDC25BADRA2A
SCHEMBL6032655 0.81 BRD4 (0.31)
SCHEMBL6149919 0.81 BRD4 (0.31)
SCHEMBL26606294 0.81
SCHEMBL4460798 0.80 HTR7 (0.38) HTR1AHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102964371-B A kind of preparation method of silicon bridge vicinal resistance type cyclopentadiene compounds SHANGHAI RESEARCH INSTITUTE OF CHEMICAL INDUSTRY (CN) 2015-08-12 CN claimed
CN-102964371-A Preparation method of silicon-bridged sterically-hindered cyclopentadiene compound SHANGHAI RES INST CHEMICAL IND 2013-03-13 CN claimed
CN-118613513-A Hybrid metallocene catalyst and method for preparing polyethylene using the same 株式会社LG化学 2024-09-06 CN disclosed
US-11993665-B2 Hybrid supported catalyst and method of preparing polyolefin using the same LG CHEM, LTD. (KR) 2024-05-28 US disclosed
CN-113039217-B Hybrid supported catalyst and method for preparing polyolefin using the same 株式会社LG化学 2023-05-12 CN disclosed
US-20220017657-A1 Hybrid Supported Catalyst and Method of Preparing Polyolefin Using the Same LG CHEM, LTD. (KR) 2022-01-20 US disclosed
EP-3865517-A1 SUPPORTED HYBRID CATALYST AND METHOD FOR PREPARING POLYOLEFIN BY USING SAME LG Chem, Ltd. (KR) 2021-08-18 EP disclosed
CN-113039217-A Hybrid supported catalyst and method for preparing polyolefin using the same 株式会社LG化学 2021-06-25 CN disclosed
WO-2021060908-A1 SUPPORTED HYBRID CATALYST AND METHOD FOR PREPARING POLYOLEFIN BY USING SAME 주식회사 엘지화학 2021-04-01 WO disclosed
US-10005864-B2 Metallocene compound, catalyst for olefin polymer, method for producing olefin polymer, and olefin polymer JAPAN POLYETHYLENE CORPORATION (JP) 2018-06-26 US disclosed
EP-3078670-B1 METALLOCENE COMPOUND, CATALYST FOR OLEFIN POLYMER, METHOD FOR PRODUCING OLEFIN POLYMER, AND OLEFIN POLYMER JAPAN POLYETHYLENE CORP (JP) 2017-12-27 EP disclosed
EP-0834519-B1 CATALYST FOR POLYOLEFIN PRODUCTION AND PROCESS FOR PRODUCING POLYOLEFIN JAPAN POLYOLEFINS CO LTD (JP) 2002-03-06 EP disclosed
EP-1141034-A2 BRIDGED METAL COMPLEXES FOR GAS PHASE POLYMERIZATIONS BP Chemicals Limited (GB) 2001-10-10 EP disclosed
US-6284905-B1 GROUP 4 TRANSITION METAL COMPLEX CONTAINING A BORON OR ALUMINUM BRIDGING GROUP CONTAINING A NITROGEN CONTAINING ELECTRON DONATING GROUP, ESPECIALLY AN AMIDO GROUP; OLEFIN SOLUTION OR SLURRY POLYMERIZATION CATALYSTS THE DOW CHEMICAL COMPANY 2001-09-04 US disclosed
EP-1119575-A1 BRIDGED METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 2001-08-01 EP disclosed
WO-2001048034-A2 TRANSITION METAL COMPOUND, LIGAND SYSTEM, CATALYST SYSTEM AND THE USE OF THE LATTER FOR THE POLYMERISATION AND COPOLYMERISATION OF OLEFINS BASELL POLYOLEFINE GMBH (DE) 2001-07-05 WO disclosed
US-6121182-A A METALLOCENE CATALYST FOR POLYMERIZATION OF ISOTACTIC POLYOLEFINS WITH HIGH RIGIDITY AND HIGH MELTING POINT, USEFUL AS INDUSTRIAL MATERIAL FOR AUTOMOBILES JAPAN POLYOLAFINS CO., LTD. (JP) 2000-09-19 US disclosed
WO-2000020462-A2 BRIDGED METAL COMPLEXES FOR GAS PHASE POLYMERIZATIONS BP CHEMICALS LIMITED (GB) 2000-04-13 WO disclosed
WO-2000020426-A1 BRIDGED METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 2000-04-13 WO disclosed
EP-0834519-A1 CATALYST FOR POLYOLEFIN PRODUCTION AND PROCESS FOR PRODUCING POLYOLEFIN Japan Polyolefins Co., Ltd. (JP) 1998-04-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10005864-B2 Metallocene compound, catalyst for olefin polymer, method for producing olefin polymer, and olefin polymer CPNE4, PPOX, PIN1 PRCP 3981/4885HTR1A 2224/4885HTR7 2881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.