Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CLK1 | P49759 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10676534 | 0.82 | PTAFR (0.62) | KMT2AMEN1 | |
| SCHEMBL8636926 | 0.80 | NPC1 (0.70) | KMT2AMEN1SLC6A5HPGDSMN1; SMN2 | |
| SCHEMBL8548802 | 0.79 | NPC1 (0.72) | KMT2AMEN1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL31372428 | 0.79 | GAA (0.54) | KMT2AMEN1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL8205935 | 0.78 | SIRT2 (0.50) | KMT2AMEN1HPGDNPC1RAB9A | |
| SCHEMBL13753817 | 0.77 | HPGD (0.52) | KMT2AHPGDALDH1A1KDM4EUSP2 | |
| SCHEMBL28489579 | 0.77 | NPC1 (0.72) | KMT2AMEN1SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL20556477 | 0.76 | NOS2 (0.63) | KMT2AMEN1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL17554117 | 0.75 | ABCG2 (0.63) | KMT2AMEN1SLC6A5HPGDSMN1; SMN2 | |
| SCHEMBL30560465 | 0.75 | ABCG2 (0.63) | KMT2AMEN1SLC6A5HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399423-A2 | ANTHRANILIC ACID AMIDES WITH A HETEROARYLSULFONYL SIDE CHAIN, METHOD FOR THE PRODUCTION THEREOF, USE THEREOF AS A MEDICAMENT OR DIAGNOSTIC AGENT AND PHARMACEUTICAL PREPARATIONS CONTAINING SAID COMPOUNDS | Aventis Pharma Deutschland GmbH (DE) | 2004-03-24 | — | — | EP | disclosed |
| WO-2002100825-A2 | ANTHRANILIC ACID AMIDES WITH A HETEROARYLSULFONYL SIDE CHAIN, AND USE THEREOF AS ANTIARRHYTHMIC ACTIVE SUBSTANCES | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |