Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6187334 | 0.81 | FFAR1 (0.46) | SIRT2FFAR1MTNR1BMTNR1AS1PR1 | |
| SCHEMBL6909753 | 0.78 | KMT2A (0.55) | MTNR1BMTNR1AMEN1KMT2ANPC1 | |
| SCHEMBL8206423 | 0.76 | CYP1A2 (0.49) | SIRT2MTNR1BMTNR1ACYP1A2CYP2C9 | |
| SCHEMBL8199077 | 0.75 | BRAF (0.51) | MEN1KMT2ACYP1A2CYP2C9NPC1 | |
| SCHEMBL312285 | 0.74 | FFAR1 (0.59) | SIRT2FFAR1S1PR1S1PR3MAOA | |
| SCHEMBL29706545 | 0.74 | FFAR1 (0.59) | SIRT2FFAR1S1PR1S1PR3MAOA | |
| SCHEMBL6185416 | 0.74 | SIRT2 (0.45) | SIRT2FFAR1MTNR1BMTNR1AS1PR1 | |
| SCHEMBL8206774 | 0.74 | CASP3 (0.47) | SIRT2NPC1RAB9AMAOAMCL1 | |
| SCHEMBL7909139 | 0.73 | MAOB (0.56) | FFAR1MEN1KMT2AMAOAMAOB | |
| SCHEMBL23882144 | 0.73 | ALDH1A1 (0.46) | MEN1KMT2AHPGDMCL1BCL2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979227-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2000-02-16 | — | — | EP | disclosed |
| WO-1998047882-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-29 | — | — | WO | disclosed |