Hydrochloric Acid

Hydrochloric Acid

SCHEMBL6909767

CC(C)=[Zr+2](C1C(c2ccccc2)=Cc2ccccc21)C1C(c2ccccc2)=Cc2ccccc21.[Cl-].[Cl-]

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 3/20 0.35
CYP11B2 P19099 3/20 0.35
CYP19A1 P11511 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7637755 0.93 CYP11B1 (0.32) CYP11B1CYP11B2CYP19A1
Hydrochloric Acid SCHEMBL5004296 0.88 ALDH1A1 (0.32) CYP11B1CYP11B2CYP19A1
Hydrochloric Acid SCHEMBL7932954 0.83 LMNA (0.33) CYP11B1CYP11B2CYP19A1
Hydrochloric Acid SCHEMBL7640280 0.79 BRD4 (0.31)
Hydrochloric Acid SCHEMBL436801 0.78 ALDH1A1 (0.32)
Hydrochloric Acid SCHEMBL31676791 0.78 ALDH1A1 (0.32)
Hydrochloric Acid SCHEMBL3734166 0.77 CYP11B1 (0.33) CYP11B1CYP11B2CYP19A1
Hydrochloric Acid SCHEMBL29898386 0.77 CYP11B1 (0.33) CYP11B1CYP11B2CYP19A1
Hydrochloric Acid SCHEMBL965083 0.77 CYP11B1 (0.33) CYP11B1CYP11B2CYP19A1
Hydrochloric Acid SCHEMBL565364 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6790917-B2 POLYMERIZING A VINYL COMPOUND IN PRESENCE OF A CATALYST OBTAINED BY COMBINING ORGANOTRANSITION METAL COMPOUND, AN ALUMINUM COMPUND OR ALUMOXANE AND A BORON COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-09-14 US disclosed
US-20020198340-A1 Process for producing vinyl compound polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-12-26 US disclosed
US-6472490-B1 AN ETHYLENE-AROMATIC VINYL COMPOUND COPOLYMER HAVING AN AROMATIC VINYL COMPOUND CONTENT OF FROM 1 TO LESS THAN 55% BY MOLAR FRACTION, WHICH HAS A HAZE OF AT MOST 41.5% WHEN MOLDED; METHINE DYES DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2002-10-29 US disclosed
US-6348556-B1 COORDINATION CATALYST OF TRANSITION METAL COMPLEX CONTAINING INDENYL GROUP(S) AND COCATALYST; ISOTACTIC; CATALYSIS, ADDITION COPOLYMERIZATION DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2002-02-19 US disclosed
US-6066709-A Ethylene-aromatic vinyl compound copolymer and method for its production DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2000-05-23 US disclosed
US-5883213-A STEREOREGULARITY DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1999-03-16 US disclosed