SCHEMBL690985

SCHEMBL690985

CNc1nc(Cl)nc2c1ncn2CC(COC(=O)C(C)(C)C)COC(=O)C(C)(C)C

nearest known ligand 0.68

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
P2RY1 P47900 3/20 0.68
YTHDC1 Q96MU7 8/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30513029 1.00 P2RY1 (0.68) P2RY1YTHDC1
SCHEMBL29427723 0.89 P2RY1 (0.56) P2RY1YTHDC1
SCHEMBL31425733 0.82 P2RY1 (0.53) P2RY1YTHDC1
SCHEMBL14509185 0.81 P2RY1 (1.00) P2RY1
SCHEMBL23867126 0.77 P2RY1 (1.00) P2RY1YTHDC1
SCHEMBL3675889 0.75 P2RY1 (0.46) P2RY1YTHDC1
SCHEMBL20774171 0.72 P2RX7 (0.49) P2RY1YTHDC1
SCHEMBL9583418 0.71 P2RY1 (0.52) P2RY1YTHDC1
SCHEMBL14509250 0.71 P2RY1 (1.00) P2RY1YTHDC1
SCHEMBL9583890 0.70 YTHDC1 (0.60) P2RY1YTHDC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8772040-B2 Apparatus and method of platelet multi-function analysis, and micro stirring chip KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) 2014-07-08 US claimed
EP-2453926-A2 PEPTIDES WHOSE UPTAKE IN CELLS IS CONTROLLABLE The Regents of the University of California (US) 2012-05-23 EP claimed
WO-2011008996-A2 PEPTIDES WHOSE UPTAKE IN CELLS IS CONTROLLABLE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-01-20 WO claimed
US-20100183598-A1 METHODS OF TREATING CARDIOVASCULAR DISORDERS CAROLUS THERAPEUTICS, INC. (US) 2010-07-22 US claimed
WO-2010056910-A2 METHODS OF TREATING CARDIOVASCULAR DISORDERS CAROLUS THERAPEUTICS, INC. (US) 2010-05-20 WO claimed
US-20230279048-A1 COMPOSITIONS CONTAINING HC-HA/PTX3 COMPLEXES AND METHODS OF USE THEREOF U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION 2023-09-07 US disclosed
US-11518782-B2 Compositions containing HC-HA/PTX3 complexes and methods of use thereof TISSUETECH, INC. (US) 2022-12-06 US disclosed
EP-3838293-A1 COMPOSITIONS CONTAINING HC-HA/PTX3 COMPLEXES AND METHODS OF USE THEREOF Tissuetech, Inc. (US) 2021-06-23 EP disclosed
EP-2872181-B1 COMPOSITIONS CONTAINING HC-HA/PTX3 COMPLEXES AND METHODS OF USE THEREOF TISSUETECH INC (US) 2020-11-18 EP disclosed
US-20200308219-A1 COMPOSITIONS CONTAINING HC-HA/PTX3 COMPLEXES AND METHODS OF USE THEREOF U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION 2020-10-01 US disclosed
US-10717763-B2 Compositions containing HC-HA/PTX3 complexes and methods of use thereof TISSUETECH, INC. (US) 2020-07-21 US disclosed
US-10597722-B2 Predictive analysis for myocardial infarction SCRIPPS HEALTH (US) 2020-03-24 US disclosed
US-20100183598-A1 METHODS OF TREATING CARDIOVASCULAR DISORDERS CAROLUS THERAPEUTICS, INC. (US) 2010-07-22 US disclosed
WO-2010056910-A2 METHODS OF TREATING CARDIOVASCULAR DISORDERS CAROLUS THERAPEUTICS, INC. (US) 2010-05-20 WO disclosed
WO-2010042548-A2 METHODS OF TREATING INFLAMMATION CAROLUS THERAPEUTICS, INC. (US) 2010-04-15 WO disclosed
US-20100093636-A1 METHODS OF TREATING INFLAMMATION CAROLUS THERAPEUTICS, INC. (US) 2010-04-15 US disclosed
US-20070254324-A1 Method for determination of platelet function under flow conditions DADE BEHRING MARBURG GMBH 2007-11-01 US disclosed
US-20070254325-A1 Method and device for the determination of platelet function under flow conditions DADE BEHRING MARBURG GMBH 2007-11-01 US disclosed
EP-1850134-A1 Method and Apparatus for the determination of the Thromboyte function and flow conditions Dade Behring Marburg GmbH (DE) 2007-10-31 EP disclosed
EP-1850135-A1 Method for determining the thrombocyte function and flow conditions Dade Behring Marburg GmbH (DE) 2007-10-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100183598-A1 METHODS OF TREATING CARDIOVASCULAR DISORDERS TNNI3, TNNT2, FABP3 P2RY1 352/4885YTHDC1 1722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.