Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6905728 | 0.86 | PDCD1 (0.34) | PDCD1CD274EDNRBEDNRALMNA | |
| Hydrochloric Acid SCHEMBL6907076 | 0.85 | MYC (0.31) | — | |
| Hydrochloric Acid SCHEMBL6911172 | 0.80 | PDCD1 (0.33) | PDCD1CD274EDNRBEDNRA | |
| Hydrochloric Acid SCHEMBL6909394 | 0.78 | KMO (0.34) | EDNRBEDNRALMNATDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL29216496 | 0.74 | PDCD1 (0.34) | PDCD1CD274EDNRBEDNRALMNA | |
| Hydrochloric Acid SCHEMBL27516469 | 0.72 | PDCD1 (0.35) | PDCD1CD274EDNRBEDNRALMNA | |
| Hydrochloric Acid SCHEMBL6903320 | 0.71 | ALDH1A1 (0.34) | EDNRBEDNRALMNAMAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL27499114 | 0.71 | PDCD1 (0.34) | PDCD1CD274EDNRBEDNRALMNA | |
| Hydrochloric Acid SCHEMBL5689032 | 0.70 | PDCD1 (0.32) | PDCD1CD274EDNRBEDNRA | |
| Hydrochloric Acid SCHEMBL6909569 | 0.70 | PDCD1 (0.36) | PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6790917-B2 | POLYMERIZING A VINYL COMPOUND IN PRESENCE OF A CATALYST OBTAINED BY COMBINING ORGANOTRANSITION METAL COMPOUND, AN ALUMINUM COMPUND OR ALUMOXANE AND A BORON COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-09-14 | — | — | US | disclosed |
| US-20020198340-A1 | Process for producing vinyl compound polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-12-26 | — | — | US | disclosed |