Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6915490 | 0.88 | SIGMAR1 (0.42) | KCNH2OPRM1DRD3DRD2OPRD1 | |
| SCHEMBL6914843 | 0.85 | KCNH2 (0.42) | KCNH2OPRM1DRD3TDP1DRD2 | |
| SCHEMBL6904976 | 0.85 | KCNH2 (0.42) | KCNH2OPRM1DRD3TDP1DRD2 | |
| SCHEMBL6905115 | 0.79 | TP53 (0.44) | KCNH2OPRM1DRD3CHRM2HTR1A | |
| SCHEMBL6913267 | 0.72 | SIGMAR1 (0.42) | KCNH2OPRM1DRD3DRD2OPRD1 | |
| SCHEMBL6911396 | 0.70 | TSHR (0.48) | KCNH2OPRK1SLC6A2SLC6A4ADRA1A | |
| SCHEMBL172516 | 0.69 | MAPT (0.60) | KCNH2OPRM1DRD3DRD2OPRD1 | |
| SCHEMBL329300 | 0.69 | MAPT (0.66) | KCNH2OPRM1DRD3DRD2OPRD1 | |
| SCHEMBL9768710 | 0.68 | MAPT (0.63) | KCNH2OPRM1DRD3DRD2OPRD1 | |
| SCHEMBL6947636 | 0.68 | OPRM1 (0.73) | KCNH2OPRM1DRD3DRD2OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0969010-B1 | Transition metal compound and catalyst containing the same for polymerization of olefins | JAPAN POLYOLEFINS CO LTD (JP) | 2004-09-22 | — | — | EP | disclosed |
| US-6352953-B1 | TRANSITION METAL COMPLEX HAVING 5-MEMBERED RING FORMED BY TRANSITION METAL COMPOUND OF GROUP IVB, TWO CARBONS, METAL OF GROUP IIIA AND HYDROGEN | JAPAN POLYOLEFINS CO., LTD. (JP) | 2002-03-05 | — | — | US | disclosed |
| US-6150544-A | Transition metal compound and catalyst containing the same for polymerization of olefins | JAPAN POLYOLEFINS CO., LTD. (JP) | 2000-11-21 | — | — | US | disclosed |
| EP-0969010-A2 | Transition metal compound and catalyst containing the same for polymerization of olefins | Japan Polyolefins Co., Ltd. (JP) | 2000-01-05 | — | — | EP | disclosed |