Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.39 |
| ▸ | HRH1 | P35367 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599440 | 0.78 | LMNA (0.46) | HTR2AHRH1LMNATAAR1TDP1 | |
| SCHEMBL8599444 | 0.78 | LMNA (0.46) | HTR2AHRH1LMNATAAR1TDP1 | |
| SCHEMBL3715025 | 0.75 | HTR2A (0.46) | HTR2AHRH1LMNATAAR1TDP1 | |
| SCHEMBL7238090 | 0.74 | LMNA (0.41) | HTR2AHRH1LMNATAAR1TDP1 | |
| SCHEMBL7245503 | 0.74 | HTR2A (0.41) | HTR2AHRH1LMNATAAR1TDP1 | |
| SCHEMBL7244292 | 0.74 | HTR2A (0.41) | HTR2AHRH1LMNATAAR1TDP1 | |
| SCHEMBL5405865 | 0.74 | LMNA (0.41) | HTR2AHRH1LMNATAAR1TDP1 | |
| SCHEMBL7244288 | 0.74 | HTR2A (0.41) | HTR2AHRH1LMNATAAR1TDP1 | |
| SCHEMBL5405861 | 0.74 | LMNA (0.41) | HTR2AHRH1LMNATAAR1TDP1 | |
| SCHEMBL5853849 | 0.73 | LMNA (0.42) | HTR2AHRH1LMNATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6743872-B1 | STABLE THREE MEMBERED TITANACARBOCYCLE; REACTING DIALKYL-TITANIUM DICHLORIDE WITH OLEFINIC OR ACETYLENIC COMPONENT | THE RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK | 2004-06-01 | — | — | US | disclosed |