Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 7/20 | 0.41 |
| ▸ | HRH1 | P35367 | 6/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599444 | 1.00 | LMNA (0.46) | LMNAHTR2AHRH1TAAR1TDP1 | |
| SCHEMBL10640638 | 0.85 | LMNA (0.42) | LMNAHTR2AHRH1TAAR1POLB | |
| SCHEMBL10640640 | 0.85 | LMNA (0.42) | LMNAHTR2AHRH1TAAR1POLB | |
| SCHEMBL10644867 | 0.83 | TAAR1 (0.48) | LMNAHTR2ATAAR1TRPA1 | |
| SCHEMBL10644871 | 0.83 | TAAR1 (0.48) | LMNAHTR2ATAAR1TRPA1 | |
| SCHEMBL28144387 | 0.81 | LMNA (0.57) | LMNATAAR1 | |
| SCHEMBL7404409 | 0.79 | HTR2A (0.43) | LMNAHTR2AHRH1TAAR1TDP1 | |
| SCHEMBL6910264 | 0.78 | HTR2A (0.39) | LMNAHTR2AHRH1TAAR1TDP1 | |
| SCHEMBL27759532 | 0.78 | CHRNB2 (0.41) | LMNAHTR2AHRH1TDP1 | |
| SCHEMBL16103786 | 0.78 | LMNA (0.44) | LMNAPOLBTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0715613-B1 | NEW DIPHENYLHEXENE | PECHAN REINHARD (DE) | 1998-01-28 | — | — | EP | disclosed |
| US-5650445-A | Diphenylhexene composition for use in treating liver carcinoma and psoriasis | PECHAN REINHARD (DE) | 1997-07-22 | — | — | US | disclosed |
| US-5578742-A | INHIBIT UNCONTROLLED CELL PROLIFERATION, TREATMENT OF PSORIASIS, AIDS, CANCER, ANTITUMOR | METZLER MANFRED (DE) | 1996-11-26 | — | — | US | disclosed |
| EP-0636115-B1 | NOVEL BIS-PHENYL-HEXENES | METZLER MANFRED (DE) | 1996-08-14 | — | — | EP | disclosed |
| EP-0715613-A1 | NEW DIPHENYLHEXENE | PECHAN, Reinhard (DE) | 1996-06-12 | — | — | EP | disclosed |
| WO-1995006020-A1 | NEW DIPHENYLHEXENE | PECHAN REINHARD (DE) | 1995-03-02 | — | — | WO | disclosed |
| EP-0636115-A1 | NOVEL BIS-PHENYL-HEXENES. | METZLER MANFRED (DE) | 1995-02-01 | — | — | EP | disclosed |
| WO-1993022262-A1 | NOVEL BIS-PHENYL-HEXENES | METZLER MANFRED (DE) | 1993-11-11 | — | — | WO | disclosed |